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58 results
  • Metachronic Breast and Cerebellar Neoplasm in a Young Patient. [Journal Article]
    Rev Bras Ginecol Obstet. 2020 Feb; 42(2):114-119.Nascimento JO, Haro LCA, … Storch RE
  • Several factors trigger the development of genetic mutations that are responsible for causing a neoplasm. Medulloblastoma is a malignant and invasive cerebellar neoplasm, that affects children and young adults. Mucinous carcinoma is a special type of breast cancer. Being a special atypical subtype of invasive carcinoma, it most frequently affects women of advanced age and represents 1 to 7% of al…
  • Signaling Pathways in Thyroid Cancer. [Journal Article]
    Vitam Horm. 2018; 106:501-515.Jin S, Yang YT, Bao W
  • The morbidity of thyroid cancer is increasing gradually year by year, showing an increasing tendency in nationality, sex, age, tumor size, and tumor staging. The changes of thyroid cell genes, signaling pathways, and related molecular dysfunction promote the occurrence, development, invasion, and metastasis of thyroid cancer. Surgical operation, radioiodine, and endocrinotherapy models can achiev…
  • MED23 in endocrinotherapy for breast cancer. [Journal Article]
    Oncol Lett. 2017 Jun; 13(6):4679-4684.Lin B, Zhang L, … Sun H
  • We investigated the role of the transcriptional mediator subunit 23 (MED23) in everolimus drug resistance, invasion and metastasis during breast cancer treatment and its molecular mechanism. We also evaluated the endocrinotherapy and prevention method for breast cancer. Breast cancer cell strains were established that can continuously express MED23, as well as inducible MED23-shRNA expression pla…
  • [Progression of diagnosis and treatment in primary malignant small bowel tumor]. [Review]
    Zhonghua Wei Chang Wai Ke Za Zhi. 2017 Jan 25; 20(1):117-120.Zhao Z, Guan X, … Wang X
  • Primary malignant small bowel tumor as a rare kind of intestinal tumor is associated with a poor prognosis. The pathological types were various and complicated, such as adenocarcinoma, neuroendocrine tumor, malignant lymphoma, and malignant stromal tumor. The atypical early stage symptom resulted in difficult diagnosis at early stage, high misdiagnosis rate and lack of standard therapy schemes an…
  • New Immunotherapy Strategies in Breast Cancer. [Review]
    Int J Environ Res Public Health. 2017 01 12; 14(1)Yu LY, Tang J, … Chen XP
  • Breast cancer is the most commonly diagnosed cancer among women. Therapeutic treatments for breast cancer generally include surgery, chemotherapy, radiotherapy, endocrinotherapy and molecular targeted therapy. With the development of molecular biology, immunology and pharmacogenomics, immunotherapy becomes a promising new field in breast cancer therapies. In this review, we discussed recent progr…
  • BRCA mutations and survival in breast cancer: an updated systematic review and meta-analysis. [Review]
    Oncotarget. 2016 Oct 25; 7(43):70113-70127.Zhu Y, Wu J, … Zhang Z
  • BRCA mutations occur frequently in breast cancer (BC), but their prognostic impact on outcomes of BC has not been determined. We conducted an updated meta-analysis on the association between BRCA mutations and survival in patients with BC. Electronic databases were searched. The primary outcome measure was overall survival (OS), and the secondary outcome measures included breast cancer-specific s…
  • Inhibiting autophagy increases epirubicin's cytotoxicity in breast cancer cells. [Journal Article]
    Cancer Sci. 2016 Nov; 107(11):1610-1621.Guo W, Wang Y, … Zheng H
  • Chemotherapy, radiotherapy, and endocrinotherapy are documented to induce autophagy among breast cancer cells, but the role of autophagy in this disease has been attributed as cytoprotective as well as tumor-suppressing. Thus we studied MDA-MB-231 and SK-BR-3 breast cancer cell lines treated with epirubicin (EPI) to assess autophagy and apoptosis. We found out that EPI induced apoptosis and autop…
  • [Staging Based Strategies and Practice for Prostate Cancer]. [Journal Article]
    Zhongguo Zhong Xi Yi Jie He Za Zhi. 2016 Jun; 36(6):749-52.Chen ZQ, Wang SS, … Zhu SL
  • Authors raised that staging based strategies and practice of integrative medicine (IM) by combining syndrome typing and disease identification, and choosing suitable measures in accordance with different persons and seasonal conditions after more than ten years' clinical practice and researches. Radical operation as prior (as evil eliminating) and strengthening vital qi in perioerative period are…
  • Neo-endocrinochemotherapy: a novel approach for enhancing chemotherapeutic efficacy in clinic? [Journal Article]
    Med Hypotheses. 2013 Apr; 80(4):441-6.Huang J, Ji G, … Kong L
  • Chemosensitization means enhancing the sensitivity of tumor cells to chemotherapy with certain methods for better efficacy. Tumor progression depends on stimulation of multiple hormones, decrease in hormones during chemotherapy induces G0/G1 arrest of tumor cells, which may be the main cause for chemoresistance. Some of the choriocarcinoma and testicular tumors are curable with chemotherapy only,…
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