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5,169 results
  • Cryo-EM structure of the CFA/I pilus rod. [Journal Article]
    IUCrJ 2019; 6(Pt 5):815-821Zheng W, Andersson M, … Egelman E
  • Enterotoxigenic Escherichia coli (ETEC) are common agents of diarrhea for travelers and a major cause of mortality in children in developing countries. To attach to intestinal cells ETEC express colonization factors, among them CFA/I, which are the most prevalent factors and are the archetypical representative of class 5 pili. The helical quaternary structure of CFA/I can be unwound under tensile…
  • A Quest of Great Importance-Developing a Broad Spectrum Escherichia coli Phage Collection. [Journal Article]
    Viruses 2019; 11(10)Kaczorowska J, Casey E, … Mahony J
  • Shigella ssp. and enterotoxigenic Escherichia coli are the most common etiological agents of diarrheal diseases in malnourished children under five years of age in developing countries. The ever-growing issue of antibiotic resistance and the potential negative impact of antibiotic use on infant commensal microbiota are significant challenges to current therapeutic approaches. Bacteriophages (or p…
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