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33,671 results
  • StatPearls: Bancroftian Filariasis [BOOK]
    StatPearls Publishing: Treasure Island (FL) Zulfiqar Hassam H Rawalpindi Medical University Waheed Abdul A Malik Ahmad A BOOK
  • Bancroftian filariasis, accounting for 90% of the lymphatic filariasis cases, is one of the most common etiology of acquired lymphedema. It is the second leading infectious cause of disability worldwide after leprosy.[1][2] The disease primarily involves lymphatic system with clinical manifestations ranging from acute, such as acute adenolymphangitis, filarial fever, tropical pulmonary eosinophil…
  • Effect Of Dual sEH/COX-2 Inhibition on Allergen-Induced Airway Inflammation. [Journal Article]
    Front Pharmacol 2019; 10:1118Dileepan M, Rastle-Simpson S, … Rao SP
  • Arachidonic acid metabolites resulting from the cyclooxygenase (COX), lipoxygenase, and cytochrome P450 oxidase enzymatic pathways play pro- and anti-inflammatory roles in allergic airway inflammation (AAI) and asthma. Expression of COX-2 and soluble epoxide hydrolase (sEH) are elevated in allergic airways and their enzymatic products (e.g., prostaglandins and diols of epoxyeicosatrienoic acids, …
  • Mepolizumab rescue therapy for acute pneumonitis secondary to DRESS. [Journal Article]
    BMJ Case Rep 2019; 12(10)Thein OS, Sutton B, … Parekh D
  • Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome represents a severe adverse drug reaction driven by eosinophilia. Treatment is focused on withdrawal of medication, supportive care and immunosuppression such as high-dose corticosteroid therapy. Here we report a 56-year-old male patient who initially presented with breathlessness and eosinophilia, subsequent development of re…
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