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157,161 results
  • Public Endowment of B Cells. [Journal Article]
    Immunity 2019; 51(4):601-603Hangartner L
  • Using a transgenic mouse strain expressing the human VH1-69 germline gene used by many broadly neutralizing antibodies to influenza A virus, Sangesland et al. show that the VH1-69 gene segment provides the essentials for mounting antibody responses against the conserved hemagglutinin stem epitope.
  • Fine epitope mapping of glycoprotein Gn in Guertu virus. [Journal Article]
    PLoS One 2019; 14(10):e0223978Zhang J, Moming A, … Sun S
  • Guertu virus (GTV) is a tick-borne phleboviruses (TBPVs) which belongs to the genus Banyangvirus in the family of Phenuiviridae. In vitro and in vivo studies of GTV demonstrated that it was able to infect animal and human cell lines and could cause pathological lesions in mice. Glycoproteins (GP, including Gn and Gc) on the surface of Guertu virus (GTV) could bind to receptors on host cells and i…
  • Seeking Flavivirus Cross-Protective Immunity. [Journal Article]
    Front Immunol 2019; 10:2260Dos Santos Franco L, Gushi LT, … Amorim JH
  • The Flavivirus genus is composed by viral serocomplexes with relevant global epidemiological impact. Many areas of the world present both, vector fauna and geographical conditions compatible with co-circulation, importing, emergence, and epidemics of flaviviruses of different serocomplexes. In this study, we aimed to identify both, immunological determinants and patterns of immune response possib…
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