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3,093 results
  • Severe anemia may not be a contraindication to debridement in a Jehovah's witness patient with necrotizng fasciitis of the lower extremity - A case report. [Journal Article]
    Int J Surg Case Rep 2019; 63:27-30Ogedegbe C, Fernando J, Kaul S
  • CONCLUSIONS: This case highlights some of the challenges involved in managing necrotizing fasciitis. The conversation with the Jehovah's Witness patient in a life-threatening condition must be held with the upmost respect. Surgical decision making and operative technique is critical in determining the boundary of excisional debridement to perform in the absence of the ability to transfuse blood. The medical management was focused on resuscitation for sepsis, severe anemia, hyperglycemia, and wound management.Severely anemic patients in critical condition can survive necrotizing fasciitis with a well-planned interdisciplinary approach without compromising patient autonomy.
  • Biosimilar Erythropoiesis-Stimulating Agents in Chronic Kidney Disease. [Review]
    Adv Chronic Kidney Dis 2019; 26(4):267-271Shah HH, Fishbane S
  • Anemia is a well-known complication of advanced CKD and treatment with erythropoietin analogues (epoetin) remains a key component of management. Although biologic agents, including epoetin, play an extremely important role in the treatment of various medical conditions, their cost can be prohibitive. As a result, several biosimilar agents have now been approved by the U.S. Food and Drug Administr…
  • Cytokines and Growth Factors. [Journal Article]
    Adv Biochem Eng Biotechnol 2019Silva AC, Lobo JMS
  • Several cytokines have been used to treat autoimmune diseases, viral infections, and cancer and to regenerate the skin. In particular, interferons (INFs) have been used to treat cancer, hepatitis B and C, and multiple sclerosis, while interleukins (ILs) and tumor necrosis factors (TNFs) have been used in the management of different types of cancer. Concerning the hematopoietic growth factors (HGF…
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