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44 results
  • Dermoscopic Features of a Digital Myxoid Cyst. [Case Reports]
    Acta Dermatovenerol Croat. 2019 Jun; 27(2):129-130.Monteagudo-Sánchez B, Luiña-Méndez L, Mosquera-Fernández A
  • Dear Editor, We report a case of a patient admitted to our Department presenting a typical digital myxoid cyst. A 54-year-old man was referred by his general practitioner to the Department of Dermatology at our hospital due to the presence of an asymptomatic lesion on the third right toe. Physical examination revealed a rounded, red-bluish lesion in the eponychium less than 0.5 cm in diameter wit…
  • Curling Cuticles of the Great Toenails: A Case Report of Eponychogryphosis. [Case Reports]
    Cureus. 2019 Jan 25; 11(1):e3959.Cohen PR
  • The cuticle, also referred to as the eponychium, creates a seal between the proximal nail fold and the nail plate. It is derived from both the ventral and dorsal portions of the proximal nail fold. In addition to its principle function as a barrier preventing allergens, irritants and pathogens from entering the nail cul-de-sac, the cuticle can play a role as a model for evaluating the etiology an…
  • Clinical utility of biomarkers of the hand in the diagnosis of schizophrenia. [Journal Article]
    Psychiatry Res. 2018 02; 260:105-110.Domany Y, Levy A, … Shamir EZ
  • A number of biomarkers were assessed in photos and prints of the hands of 95 patients with a variety of mental disorders to determine whether patients with schizophrenia could be distinguished from the others. Patients were recruited as consecutive admissions from an outpatient psychiatric day hospital population. Fourteen patients were diagnosed with schizophrenia/schizoaffective disorder and 81…
  • Melanocytes Pattern in the Normal Nail, With Special Reference to Nail Bed Melanocytes. [Journal Article]
    Am J Dermatopathol. 2018 Mar; 40(3):180-184.Perrin C, Michiels JF, … Ambrosetti D
  • Previous studies of the density of melanocytes in the normal nail bed have had conflicting results. This is unfortunate because knowing the normal values might help the difficult distinction between a benign subungual melanotic macule and an early melanoma in situ. Five specimens of normal nail unit were analyzed. On hematoxylin and eosin-stained sections the melanocytes were undetectable. We def…
  • StatPearls: Fingertip Injuries [BOOK]
    . StatPearls Publishing: Treasure Island (FL) Pencle Fabio J. FJ Waseem Muhammad M Lincoln Medical Center / SGU BOOK
  • The fingertip is the most distal portion of the finger providing the tactile and sensory functions that are then relayed to the brain. It is anatomically defined as the portion of finger distal to the insertion of the flexor digitorum superficialis and extensor tendons on the distal phalanx, or the interphalangeal joint when referring to the thumb. The neurovascular supply of the fingertip is via…
  • Anatomy of the nail unit and the nail biopsy. [Journal Article]
    Semin Cutan Med Surg. 2015 Jun; 34(2):95-100.Haneke E
  • The nail unit is the largest and a rather complex skin appendage. It is located on the dorsal aspect of the tips of fingers and toes and has important protective and sensory functions. Development begins in utero between weeks 7 and 8 and is fully formed at birth. For its correct development, a great number of signals are necessary. Anatomically, it consists of 4 epithelial components: the matrix…
  • Nail anatomy. [Journal Article]
    Clin Dermatol. 2013 Sep-Oct; 31(5) Berker D
  • The nail unit comprises the nail plate, the surrounding soft tissues, and their vasculature and innervation based upon the distal phalanx. The nail plate is a laminated keratinized structure lying on the nail matrix (15-25%), the nail bed with its distal onychodermal band (75-85%), and the hyponychium at its free edge. The distal part of the matrix, the lunula characterized by its half-moon shape…
  • [Treatment of paronychia]. [Journal Article]
    Oper Orthop Traumatol. 2011 Jul; 23(3):204-12.Langer MF, Lötters E, … Surke C
  • The procedure is selected based on the stage of infection with careful removal of the focal infection in the area of the nail fold.
  • Nutrition and nail disease. [Journal Article]
    Clin Dermatol. 2010 Jul-Aug; 28(4):420-5.Cashman MW, Sloan SB
  • The nail is a specialized keratinous skin appendage that grows approximately 2 to 3 mm per month, with complete replacement achieved in 6 to 9 months. Although this structure can be easily overlooked, nail disorders comprise approximately 10% of all dermatologic conditions. This contribution first provides an overview on the basic anatomy of the nail that will delineate between the nail unit (eg,…
  • Sporotrichosis of the upper extremity. [Case Reports]
    Orthopedics. 2010 Apr; 33(4)Milby AH, Pappas ND, … Bozentka DJ
  • This article presents a case of a chronic, nonhealing thumb wound in a patient with diabetes mellitus. A 67-year-old right-hand-dominant man presented with progressive erythema and swelling of the right thumb several months after sustaining a paper cut along the eponychium. The patient had already completed an extensive laboratory evaluation, including bacterial and fungal cultures, as well as a …
  • [One-stage toenail lengthening: a report of 9 cases]. [Journal Article]
    Zhongguo Gu Shang. 2008 Jan; 21(1):47-8.Zhang GL, Guo A, … Yu H
  • CONCLUSIONS: One-stage toenail lengthening in free second toe transfer for reconstruction of the thumb (finger), which can obtain a satisfactory appearance of the nail and have no influence on the motion of the reconstruction thumb (finger), is a simple and an effective operative procedure.
  • Expression of follicular sheath keratins in the normal nail with special reference to the morphological analysis of the distal nail unit. [Journal Article]
    Am J Dermatopathol. 2007 Dec; 29(6):543-50.Perrin C
  • CONCLUSIONS: The nail bed epithelium is an independent, specialized, epithelial structure with a true basal layer presenting a heterogeneous but significant proliferative activity. The so-called horny layer of the nail bed corresponds, in fact, to the superficial cells of the spinous layer of the nail bed. In this zone, the intercellular "spines" are barely detectable between cells replete with pink to brightly eosinophilic cytoplasm. The interlocking of the inferior border of the nail plate and the surface of the bed explain the strong attachment between the two tissues. The nail isthmus represents a transitional zone between the nail bed and the HYN and exhibits a pattern of keratinization different from the HYN. The cornified layer of the nail isthmus closely adheres to the undulating inferior surface of the nail plate; the two grow forward together. Therefore, the horny layer of the nail isthmus offers an effective sealing of the distal nail bed, preventing onycholysis. The terms matricial keratinization and onycholemmal keratinization could describe, respectively, the keratinization of the matrix and the nail isthmus.
  • The transverse figure-of-eight suture for securing the nail. [Journal Article]
    J Hand Surg Am. 2007 Jan; 32(1):124-5.Bristol SG, Verchere CG
  • Various techniques have been described for securing the nail plate back in its anatomic position after trauma or for reconstructive exposure. The figure-of-eight suture technique uses the paronychial folds and notches in the distal aspect of the nail plate to create both ventral and proximal forces to secure the nail plate under the eponychial fold. The transverse figure-of-eight suture prevents …
  • [Familial glomus tumor encountered in the same finger and localization in four family members]. [Case Reports]
    Acta Orthop Traumatol Turc. 2005; 39(4):365-8.Kuru I, Oktar SO, … Bozan ME
  • A 35-year-old man was referred to our clinic by a neurosurgeon for hypersensitivity and severe pain in his right middle finger. History showed that the symptoms had been present for three years and he had made several attempts to seek medical attention. A sensitive, very painful mass was palpated under the eponychium of his right middle finger. The tumor was surgically removed and histological ex…
  • Expression of hair keratins in the adult nail unit: an immunohistochemical analysis of the onychogenesis in the proximal nail fold, matrix and nail bed. [Journal Article]
    Br J Dermatol. 2004 Aug; 151(2):362-71.Perrin C, Langbein L, Schweizer J
  • CONCLUSIONS: The coexpression of hHb5 with K5 and K17 in the uppermost cell layers of the basal compartment and the lowermost layers of the keratogenous zone of the ventral matrix prompts us to designate this region the prekeratogenous zone of the ventral matrix. The two alternating types of histology and keratin expression in the dorsal matrix identify this region as a transitional zone between the eponychium and the apical matrix. Finally, our data clearly show that the ventral matrix is the main source of the nail plate. In addition, the mixed scenario of hair and epithelial keratins, including demonstrable amounts of K10, in superficial cells of the apical matrix, lends support to the notion that the dorsal portion of the nail is generated by the apical matrix.
  • Microvascularization of the human digit as studied by corrosion casting. [Journal Article]
    J Anat. 2004 Feb; 204(2):123-31.Sangiorgi S, Manelli A, … Raspanti M
  • The aim of this study was to describe microcirculation in the human digit, focusing on the vascular patterns of its cutaneous and subcutaneous areas. We injected a functional supranumerary human thumb (Wassel type IV) with a low-viscosity acrylic resin through its digital artery. The tissues around the vessels were then digested in hot alkali and the resulting casts treated for scanning electron …
  • Postural changes in capillary pressure in the hallux of healthy volunteers. [Clinical Trial]
    J Appl Physiol (1985). 2003 Dec; 95(6) Graaff JC, Ubbink DT, … Jacobs MJ
  • Capillary circulation is delicately regulated by microvascular constriction mechanisms, thereby controlling capillary perfusion and transmural pressure. The influence of posture on capillary flow has been investigated in both diseased and healthy people. However, its influence on capillary pressure has rarely been investigated. We measured capillary pressures in the supine and sitting positions i…
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