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1,181 results
  • Drugs and Lactation Database (LactMed): Eptifibatide [BOOK]
    National Library of Medicine (US): Bethesda (MD)BOOK
  • No published information is available on the use of eptifibatide during breastfeeding. Because eptifibatide is a peptide, absorption by the infant is unlikely because it is probably destroyed in the infant's gastrointestinal tract. Until more data become available, eptifibatide should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant. If it is used by…
  • From Snake Venom's Disintegrins and C-Type Lectins to Anti-Platelet Drugs. [Review]
    Toxins (Basel) 2019; 11(5)Lazarovici P, Marcinkiewicz C, Lelkes PI
  • Snake venoms are attractive natural sources for drug discovery and development, with a number of substances either in clinical use or in research and development. These drugs were developed based on RGD-containing snake venom disintegrins, which efficiently antagonize fibrinogen activation of αIIbβ3 integrin (glycoprotein GP IIb/IIIa). Typical examples of anti-platelet drugs found in clinics are …
  • Adjuvant antithrombotic therapy in ST-elevation myocardial infarction: A narrative review. [Review]
    Rev Port Cardiol 2019; 38(4):289-297Caldeira D, Pereira H
  • This article reviews the major pharmacologic features of, and clinical evidence on, adjuvant medical therapy in patients with ST-elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention. These drugs include oral antiplatelets (aspirin and P2Y12 inhibitors such as clopidogrel, prasugrel and ticagrelor), intravenous antiplatelet agents (the P2Y12 inhibitor can…
  • StatPearls: Eptifibatide [BOOK]
    StatPearls Publishing: Treasure Island (FL) Bansal Agam B. AB Cleveland Clinic, Ohio Sattar Yasar Y Icahn School of Medicine at Mount Sinai Jamil Radia T. RT Allama Iqbal Medical College BOOK
  • Eptifibatide is an antiplatelet drug which reversibly binds and inhibits glycoprotein IIb/IIIa receptor of platelets. A protein found in the venom of a southeastern pygmy rattlesnake is used to make eptifibatide. The PURSUIT and IMPACT-II account for the indications of eptifibatide by Food and Drug Administration(FDA)as mentioned below:
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