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6,618 results
  • Adjuvant treatment for resected pancreatic adenocarcinoma: A systematic review and network meta-analysis. [Review]
    Crit Rev Oncol Hematol 2019; 145:102817Parmar A, Chaves-Porras J, … Chan KKW
  • Adjuvant chemotherapy has significantly improved outcomes following surgical resection for pancreatic adenocarcinoma; however, the optimal adjuvant strategy remains unclear. This systematic review and network meta-analysis was conducted to provide indirect comparative evidence across adjuvant chemotherapies. Electronic searches of EMBASE, MEDLINE, Cochrane and ASCO databases were conducted to ide…
  • Carbazole derivatives as kinase-targeting inhibitors for cancer treatment. [Journal Article]
    Mini Rev Med Chem 2020Jessica C, Domenico I, … Stefania SM
  • Protein Kinases (PKs) are a heterogeneous family of enzymes that modulate several biological pathways, including cell division, cytoskeletal rearrangement, differentiation and apoptosis. In particular, due to their crucial role during human tumorigenesis and cancer progression, PKs are ideal targets for the design and development of effective and low toxic chemotherapeutics and represent the seco…
  • In silico analysis of the prognostic value of FAS mRNA in malignancies. [Journal Article]
    J Cancer 2020; 11(3):542-550Chen Z, Wu J, … Wang K
  • CONCLUSIONS: In summary, the dominant function of FAS may vary in different malignancies. FAS mRNA expression was correlated with better OS in breast cancer, gastric cancer and lung cancer, but worse OS in pancreatic cancer and AML. We also suggested that FAS mRNA expression could be a potential biomarker for cabozantinib and erlotinib.
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