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247,011 results
  • MEK1/2 as a Therapeutic Target in Sickle Cell Disease. [Journal Article]
    Int J Blood Res Disord 2019; 6Zennadi R
  • Identification of novel therapeutic targets has improved diagnostics and treatment of many diseases. Many innovative treatment strategies have been developed based on the newly identified biomarkers and key molecules. Most of the research focused on ways to manipulate signaling pathways by activating or suppressing them, validate new therapeutic targets for treatment, and epigenetic treatment of …
  • Characteristics of Gut Microbiota in Patients With Rheumatoid Arthritis in Shanghai, China. [Journal Article]
    Front Cell Infect Microbiol 2019; 9:369Sun Y, Chen Q, … Xiao L
  • Little is known regarding differences in the gut microbiomes of rheumatoid arthritis (RA) patients and healthy cohorts in China. This study aimed to identify differences in the fecal microbiomes of 66 Chinese patients with RA and 60 healthy Chinese controls. The V3-V4 variable regions of bacterial 16S rRNA genes were sequenced with the Illumina system to define the bacterial composition. The alph…
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