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13,686 results
  • Transfer and Metabolism of the Xenoestrogen Zearalenone in Human Perfused Placenta. [Journal Article]
    Environ Health Perspect 2019; 127(10):107004Warth B, Preindl K, … Buerki-Thurnherr T
  • CONCLUSIONS: Our findings suggest that exposure to ZEN (such as through consumption of ZEN-contaminated cereal-based products) during pregnancy may result in in utero exposure of the fetus, not only to ZEN but also some of its highly estrogenically active metabolites. In the light of the known affinity of ZEN and potentially co-occurring xenoestrogens to the estrogen receptor, and our results demonstrating placental transfer of ZEN and its metabolites in an ex vivo model, we recommend further research and more comprehensive assessment of gestational exposures in women.
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