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1,601 results
  • Effect of Ethosuximide on Audiogenic Epilepsy in Krushinsky-Molodkina Rats. [Journal Article]
    Bull Exp Biol Med 2019Fedotova IB, Perepelkina OV, … Poletaeva II
  • The anticonvulsant effect of ethosuximide (T-type calcium channel blocker) was evaluated in Krushinsky-Molodkina rats predisposed to audiogenic epilepsy. Ethosuximide given with drinking water (300 mg/kg/day) over 45 days slightly reduced proneness to audiogenic epilepsy and increased locomotor activity of the animals at the periphery of the open field. Neonatal administration of ethosuximide (3-…
  • A reappraisal of atypical absence seizures in children and adults: therapeutic implications. [Journal Article]
    Expert Opin Pharmacother 2019; :1-6Brigo F, Striano P, Belcastro V
  • Introduction: Atypical absences are generalized epileptic seizures typically affecting children with severe epilepsies and learning difficulties along with other seizure types. Video-EEG is essential for their diagnosis. Recently, atypical absence seizures have been reported as a hallmark of some developmental and epileptic encephalopathies. Areas covered: This is a narrative review of the litera…
  • Early clinical and EEG findings associated with the outcome in childhood absence epilepsy. [Journal Article]
    Epilepsy Behav 2019; 98(Pt A):273-278Canafoglia L, Dettori MS, … Panzica F
  • CONCLUSIONS: The assessment of electroclinical features provided only minimal prognostic indices. The enhanced outflow of frontal oscillations suggests a circuitry dysfunction significantly greater in the nonresponder to the early treatment. Seizure relapses were rare and comparable in patients who reached seizure freedom with first or second AED, indicating that the resistance to one AED does not influence the outcome.
  • StatPearls: Ethosuximide [BOOK]
    StatPearls Publishing: Treasure Island (FL) Hanrahan Brian B Vanderbilt University Medical Center Carson Robert P. RP Vanderbilt University Medical Center BOOK
  • Ethosuximide is FDA approved for the management of absence seizures in patients over 3 years of age. Currently, there are no off label uses for ethosuximide, however, there is some evidence it may have some analgesic effects. Specifically, several studies have suggested value in the management of neuropathic pain.[1][2][3]
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