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1,291 results
  • Energy coupling in ABC exporters. [Journal Article]
    Res Microbiol 2019van Veen HW, Singh H, … Guffick C
  • Multidrug transporters are important and interesting molecular machines that extrude a wide variety of cytotoxic drugs from target cells. This review summarizes novel insights in the energetics and mechanisms of bacterial ATP-binding cassette multidrug transporters as well as recent advances connecting multidrug transport to ion and lipid translocation processes in other membrane proteins.
  • Factors Related to Meniscal Extrusion and Cartilage Lesions in Medial Meniscus Root Tears. [Journal Article]
    J Knee Surg 2019Jeon SW, Jung M, … Kim SH
  • The purpose of this study was to identify factors affecting medial meniscus extrusion and cartilage degeneration in medial meniscus root tears (MMRT) and to determine the optimal cut-off values for the factors that predict disease severity. We retrospectively evaluated 86 consecutive patients diagnosed with an isolated MMRT by magnetic resonance imaging (MRI) examinations and arthroscopic procedu…
  • Cerebrovascular endothelial cells form transient Notch-dependent cystic structures in zebrafish. [Journal Article]
    EMBO Rep 2019; 20(8):e47047Kugler EC, van Lessen M, … Chico TJ
  • We identify a novel endothelial membrane behaviour in transgenic zebrafish. Cerebral blood vessels extrude large transient spherical structures that persist for an average of 23 min before regressing into the parent vessel. We term these structures "kugeln", after the German for sphere. Kugeln are only observed arising from the cerebral vessels and are present as late as 28 days post fertilizatio…
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