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315,760 results
  • Predicted economic damage from a quick, simple Alzheimer's disease cure. [Journal Article]
    Med Hypotheses 2019; 133:109398Norins LC
  • The estimated 5.8 million Alzheimer's disease patients in the U.S. require an enormous share of national healthcare expenditures. Other nations face similar economic burdens. There have been great efforts, thus far unsuccessful, to discover an effective therapeutic, with 1081 Alzheimer's disease drug trials completed as of May 2019. The pessimism thus engendered has forestalled contingency planni…
  • Can abiotic stresses in plants be alleviated by manganese nanoparticles or compounds? [Review]
    Ecotoxicol Environ Saf 2019; 184:109671Ye Y, Medina-Velo IA, … Gardea-Torresdey JL
  • Abiotic stress has become one of the most challenging problems for agriculture as the world population keeps increasing dramatically. Crop stress management using manganese (Mn) compounds has been recently employed to reduce the negative effects caused by drought, harsh temperature, and salinity. In response to abiotic stress, an adequate supply of Mn has shown to remediate plant manganese defici…
  • Reconstructing Denisovan Anatomy Using DNA Methylation Maps. [Journal Article]
    Cell 2019; 179(1):180-192.e10Gokhman D, Mishol N, … Carmel L
  • Denisovans are an extinct group of humans whose morphology remains unknown. Here, we present a method for reconstructing skeletal morphology using DNA methylation patterns. Our method is based on linking unidirectional methylation changes to loss-of-function phenotypes. We tested performance by reconstructing Neanderthal and chimpanzee skeletal morphologies and obtained >85% precision in identify…
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