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229,225 results
  • Skin infections in Australian Aboriginal children: a narrative review. [Review]
    Med J Aust 2019Davidson L, Knight J, Bowen AC
  • Impetigo, scabies, cellulitis and abscesses are common in Australian Aboriginal children. These conditions adversely affect wellbeing and are associated with serious long term sequelae, including invasive infection and post-infectious complications, such as acute post-streptococcal glomerulonephritis and acute rheumatic fever, which occurs at the highest documented rates in the world in remote Ab…
  • Cranial melioidosis presenting as osteomyelitis and/or extra-axial abscess: Literature review. [Review]
    World Neurosurg 2019Prasad GL
  • CONCLUSIONS: Cranial melioidosis presenting as OSEAA is associated with good outcomes, in contrast to other neurologic presentations. Intensive phase for atleast 2-3 weeks followed by maintenance phase for 3-6 months is the standard treatment, similar to other melioid presentations. High degree of suspicion and accurate identification of organism is crucial. Patients need to be monitored for recurrences, both clinically and radiologically.
  • Infective endocarditis caused by Streptococcus acidominimus. [Journal Article]
    Am J Health Syst Pharm 2019Kabbara WK, Azar-Atallah S
  • CONCLUSIONS: An 81-year-old Caucasian man underwent an elective transcatheter aortic valve implantation due to his severe aortic valve stenosis. He presented to the hospital 3 weeks later with a 1-week history of fever (39ºC) that did not resolve following a 3-day course of azithromycin and a 5-day course of ciprofloxacin. Three sets of blood sample cultures were taken. Empirical antimicrobial treatment was initiated to target gram-positive and gram-negative microorganisms and consisted of vancomycin 1 g intravenous (i.v.) every 12 hours and imipenem-cilastatin 500 mg i.v. every 6 hours. After 48 hours, the blood culture was positive for S. acidominimus. The strain was sensitive to ampicillin, cephalosporins, tetracycline, and vancomycin. It was resistant to penicillin, macrolides, trimethoprim-sulfamethoxazole, and fosfomycin. Transesophageal echocardiography showed a small mobile vegetation attached to the anterior mitral valve leaflet, along with mild mitral regurgitation. The patient was diagnosed with native mitral valve infective endocarditis, and imipenem-cilastatin was discontinued. The patient showed clinical and laboratory improvement during his 2-week hospitalization. A peripherally inserted central catheter was put in place, and the patient was discharged on i.v. vancomycin to complete a total of 6 weeks treatment, after which the infection resolved.An 81-year-old man diagnosed with mitral valve endocarditis caused by S. acidominimus was successfully treated with vancomycin.
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