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1,648 results
  • Sericin Inhibits Devitrification of Amorphous Drugs. [Journal Article]
    AAPS PharmSciTech 2019; 20(7):285Salunkhe N, Jadhav N, … Choudhari P
  • The purpose of the present investigation was to analyze devitrification of amorphous drugs such as lornoxicam, meloxicam, and felodipine in the presence of sericin. The binary solid dispersions comprising varying mass ratios of drug and sericin were subject to amorphization by spray drying, solvent evaporation, ball milling, and physical mixing. Further, obtained solid dispersions (SDs) were char…
  • Modelling phase separation in amorphous solid dispersions. [Journal Article]
    Acta Biomater 2019; 94:410-424Meere M, Pontrelli G, McGinty S
  • Much work has been devoted to analysing thermodynamic models for solid dispersions with a view to identifying regions in the phase diagram where amorphous phase separation or drug recrystallization can occur. However, detailed partial differential equation non-equilibrium models that track the evolution of solid dispersions in time and space are lacking. Hence theoretical predictions for the time…
  • StatPearls: Felodipine [BOOK]
    StatPearls Publishing: Treasure Island (FL) Bansal Agam B. AB Cleveland Clinic, Ohio Khandelwal Gaurav G Aiims Bhopal BOOK
  • Felodipine is an agent in the dihydropyridine class of calcium channel blockers. Felodipine is FDA approved and indicated in the treatment of essential hypertension. Reduction in blood pressure lowers the risk of cardiovascular morbidity and mortality. The most significant benefit of the antihypertensive effect of felodipine is a decrease in the incidence of stroke. In patients presenting with mi…
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