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209,202 results
  • Fine mapping epitope on glycoprotein Gc from Crimean-Congo hemorrhagic fever virus. [Journal Article]
    Comp Immunol Microbiol Infect Dis 2019; 67:101371Zhang J, Simayi A, … Sun S
  • Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne zoonosis, caused by CCHF virus (CCHFV) and which there are no diagnostic or therapeutic strategies. The C-terminus of glycoprotein (Gc) encoded by the CCHFV M gene is responsible for CCHFV binding to cellular receptors and acts as a neutralizing-antibody target. In this study, a modified biosynthetic peptide technique (BSP) was used to identi…
  • THE ACTIVITY OF AURORA KINASE B IS REQUIRED FOR DENGUE VIRUS RELEASE. [Journal Article]
    Virus Res 2019; :197777Perez-Olais JH, Ruiz-Jimenez F, … Del Angel RM
  • Flaviviruses, such as Dengue (DENV), Zika, Yellow Fever, Japanese Encephalitis and West Nile are important pathogens with high morbidity and mortality. The last estimation indicates that ∼390 millions of people are infected by DENV per year. The DENV replicative cycle occurs mainly in the cytoplasm of the infected cells and different cytoplasmic, nuclear and mitochondrial proteins participate in …
  • Flavivirus Infection- A Review of Immunopathogenesis, Immunological Response, and Immunodiagnosis. [Review]
    Virus Res 2019; :197770Chong HY, Leow CY, … Leow CH
  • Flaviviruses are group of single stranded RNA viruses that cause severe endemic infection and epidemics on a global scale. It presents a significant health impact worldwide and the viruses have the potential to emerge and outbreak in a non-endemic geographical region. Effective vaccines for prophylaxis are only available for several flaviviruses such as Yellow Fever virus, Tick-borne Encephalitis…
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