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383 results
  • Parthenolide Covalently Targets and Inhibits Focal Adhesion Kinase in Breast Cancer Cells. [Journal Article]
    Cell Chem Biol 2019; 26(7):1027-1035.e22Berdan CA, Ho R, … Nomura DK
  • Parthenolide, a natural product from the feverfew plant and member of the large family of sesquiterpene lactones, exerts multiple biological and therapeutic activities including anti-inflammatory and anti-cancer effects. Here, we further study the parthenolide mechanism of action using activity-based protein profiling-based chemoproteomic platforms to map additional covalent targets engaged by pa…
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