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1,962 results
  • Spontaneous intra-adrenal massive hematoma: possible extreme evolution of a non-secreting untreated adrenal adenoma. [Case Reports]
    J Surg Case Rep. 2020 Jun; 2020(6):rjaa185.Mancini M, Leone N, … in collaboration with European Reference Network for Rare Urogenital Diseases and Complex Conditions (ERN eUROGEN)
  • The spontaneous adrenal hematoma is a rare event. An 83-year-old male patient presented a 26-cm asymptomatic retroperitoneal mass of doubtful renal-adrenal origin. He had been evaluated 10 years before for an adrenal incidentaloma of 2.3 cm and had refused surgery when it had reached 7 cm. Later, the mass enlarged to 26 cm and was surgically removed through an open anterior approach. The histopat…
  • Chondrodermatitis nodularis nasi. [Case Reports]
    J Cutan Pathol. 2020 Jun 23 [Online ahead of print]Kasitinon SY, Vandergriff T
  • Chondrodermatitis nodularis helicis is a relatively common ulcerative, inflammatory condition affecting the skin and cartilage of the ear. We present a case of chondrodermatitis affecting the skin and cartilage of the nose, designated chondrodermatitis nodularis nasi. Clinically, chondrodermatitis presents as a singular, painful, ulcerated papule or nodule that results from prolonged pressure, tr…
  • Granular necrosis: a distinctive form of cell death in malignant tumours. [Review]
    Pathology. 2020 Jun 16 [Online ahead of print]Samaratunga H, Delahunt B, … Egevad L
  • Foci of necrosis are frequently seen in malignant tumours and may be due to a variety of causes. Different types of necrosis are given various names based upon their morphological features and presumed pathogenesis, such as coagulative, liquefactive and fibrinoid necrosis. Here, we propose the term 'granular necrosis' (GN) for a specific form of tumour necrosis characterised by the presence of we…
  • A review of the epidemiological, clinical, and pathological aspects of malignant catarrhal fever in Brazil. [Review]
    Braz J Microbiol. 2020 Jun 15 [Online ahead of print]Headley SA, de Oliveira TES, Cunha CW
  • Sheep-associated malignant catarrhal fever (SA-MCF), the form of MCF that occurs in Brazil, is a severe, frequently fatal, infectious disease caused by ovine gammaherpesvirus-2 (OvHV-2), in which sheep are the asymptomatic hosts and cattle and other cloven-hoofed animals are the accidental hosts. This review provides a critical analysis of the historical, epidemiological aspects and the estimated…
  • How to improve the histopathological diagnosis of systemic vasculitides in daily practice? [Journal Article]
    Cesk Patol. 2020 Spring; 56(2):68-73.Honsová E
  • The most common group of systemic vasculitides in adulthood are anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). AAV represent autoimmune systemic vasculitides and include 3 clinical phenotypes: Granulomatosis with polyangiitis (GPA, formerly Wegener granulomatosis), Microscopic polyangiitis (MPA) and Eosinophilic granulomatosis with polyangiitis (EGPA, formerly Churg-Stra…
  • StatPearls: Pulmonary Regurgitation [BOOK]
    . StatPearls Publishing: Treasure Island (FL) Saji Anu M. AM Father Muller Medical College Hospital Sharma Saurabh S Guthrie Robert Packer Hospital BOOK
  • The pulmonary valve directs blood from the right ventricle (RV) towards the pulmonary arteries during systole. Equally important is its closure during diastole to prevent the reversal of flow into the right ventricle driven by the drop in right ventricular pressure. Any pathology associated with its structure or function can result in impedance to this forward flow. Defective coaptation of the va…
  • Giant cell aortitis. [Journal Article]
    Forensic Sci Med Pathol. 2020 May 29 [Online ahead of print]Handlos P, Uvíra M, … Handlosová K
  • Inflammatory aortic diseases are broadly classified into three categories according to the degree of inflammation: atherosclerosis, atherosclerosis with excessive inflammation, and aortitis/periaortitis. This paper presents a case of a 39-year old man with aneurysmal dilatation of thoracic aorta and aortic valve insufficiency. The aortic wall showed thickening and wrinkled "tree bark" appearance …
  • Clinical Features and Experimental Models of Cerebral Small Vessel Disease. [Review]
    Front Aging Neurosci. 2020; 12:109.Shindo A, Ishikawa H, … Tomimoto H
  • Cerebral small vessel disease (SVD) refers to a group of disease conditions affecting the cerebral small vessels, which include the small arteries, arterioles, capillaries, and postcapillary venules in the brain. SVD is the primary cause of vascular cognitive impairment and gait disturbances in aged people. There are several types of SVD, though arteriolosclerosis, which is mainly associated with…
  • Laryngeal Contact Ulcer. [Journal Article]
    Head Neck Pathol. 2020 May 07 [Online ahead of print]Barrena BG, Miller TM, Nelson BL
  • A 47-year-old man presented to the otolaryngology service with complaint of 6 months of intermittent globus sensation. He reported constant throat clearing and subjective lowering of his voice. Flexible nasolaryngoscopy revealed a large pedunculated mass originating from the left vocal process of the arytenoid, lying superior to the vocal fold. The patient was treated conservatively with an anti-…
  • New perspectives in the endoscopic treatment of brain purulent collections: targets, techniques, results in a case series, and overview of the literature. [Journal Article]
    Acta Neurochir (Wien). 2020 May 02 [Online ahead of print]Fiorindi A, Marton E, … Longatti P
  • CONCLUSIONS: In our experience, the use of the flexible scope proved feasible and effective in the treatment of intracranial purulent collections. Visual awareness of the internal capsule is not limited to a direct inspection of the fluid pus; it rather allows an active removal of the more solid (and perhaps more microbiologically significant) fibrinoid component, and also assists in final bleeding control and in assessing the extent of the evacuation. The steering capabilities of the fiberscope are particularly suitable for such purposes, allowing sampling the solid internal layer of the pyogenic membrane, and potentially shedding light on the actual clinical significance of this component of the abscess.
  • Renal histopathological analysis of 26 postmortem findings of patients with COVID-19 in China. [Journal Article]
    Kidney Int. 2020 07; 98(1):219-227.Su H, Yang M, … Zhang C
  • Although the respiratory and immune systems are the major targets of Coronavirus Disease 2019 (COVID-19), acute kidney injury and proteinuria have also been observed. Currently, detailed pathologic examination of kidney damage in critically ill patients with COVID-19 has been lacking. To help define this we analyzed kidney abnormalities in 26 autopsies of patients with COVID-19 by light microscop…
  • Cutaneous metaplastic synovial cyst in Ehlers-Danlos syndrome. [Case Reports]
    J Cutan Pathol. 2020 Mar 14 [Online ahead of print]Fernandez-Flores A, Barja-Lopez JM
  • Classic Ehlers-Danlos syndrome (EDS) is a connective tissue disorder characterized by laxity. The skin, as one of the organs involved, shows hyperextensibility, which makes it prone to trauma. In this context, it would seem logical for cutaneous synovial metaplasia, which is considered a form of repair, to be commonly found in cases of EDS. However, there are only two previously published cases o…
  • [Pathomorphological features of the placentas and the placental sites after in vitro fertilization with a donor egg]. [Journal Article]
    Arkh Patol. 2020; 82(1):23-29.Kogan EA, Rudenko EE, … Bayanova S
  • CONCLUSIONS: The placentas and the placental sites of the women whose pregnancy occurred with IVF-S are characterized by the development of high lyoplasmacytic deciduitis activity and pronounced placental immune alterations manifested by the high incidence of immune responses at the sites of the closest contact between maternal and fetal tissues. The placental bed exhibited defective spiral artery remodeling, development of chronic inflammatory lesions in the perivascular areas, and an increase in the counts of HLA-DR positive cells and multinucleated trophoblastic giant cells.
  • SERPINA1 Peptides in Urine as A Potential Marker of Preeclampsia Severity. [Journal Article]
    Int J Mol Sci. 2020 Jan 30; 21(3)Starodubtseva N, Nizyaeva N, … Sukhikh G
  • Preeclampsia (PE) is a multisystem disorder associated with pregnancy and its frequency varies from 5 to 20 percent of pregnancies. Although a number of preeclampsia studies have been carried out, there is no consensus about disease etiology and pathogenesis so far. Peptides of SERPINA1 (α1-antitrypsin) in urine remain one of the most promising peptide markers of PE. In this study the diagnostic …
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