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28,664 results
  • StatPearls: Lysergic Acid Diethylamide (LSD, Entactogen) Toxicity [BOOK]
    StatPearls Publishing: Treasure Island (FL) Baquiran Maximo M LECOM Al Khalili Yasir Y Virginia Commonwealth University BOOK
  • D-lysergic acid diethylamide, or LSD, is a compound of the lysergamide class known for its powerful psychedelic effects on humans. Although first synthesized in 1938 by Albert Hofmann in an attempt to create a central nervous system stimulant, it was not until 1943 when Hofmann discovered the molecule’s subjective effects on the human body after accidental absorption through the skin. Only a few …
  • StatPearls: Percutaneous Liver Biopsy [BOOK]
    StatPearls Publishing: Treasure Island (FL) Chan Matthew M Albert Einstein Medical Center Navarro Victor J. VJ Sidney Kimmel Medical College BOOK
  • Percutaneous liver biopsy is a procedure where a needle is introduced through the skin and, eventually liver tissue to obtain a specimen to help aid in the diagnosis, staging, and/or the development of treatment modalities for a variety of liver disorders. The first report of the procedure was in 1923.[1] Given the advancements in imaging modalities such as ultrasound, computed tomography (CT), a…
  • Improving timely analgesia administration for musculoskeletal pain in the emergency department. [Journal Article]
    BMJ Open Qual 2020; 9(1)Woolner V, Ahluwalia R, … Chartier LB
  • Delays to adequate analgesia result in worse patient care, decreased patient and provider satisfaction and increased patient complaints. The leading presenting symptom to emergency departments (EDs) is pain, with approximately 34 000 such patients per year in our academic hospital ED and 3300 visits specific for musculoskeletal (MSK) injuries. Our aim was to reduce the time-to-analgesia (TTA; tim…
  • Prehospital trauma care evolution, practice and controversies: need for a review. [Journal Article]
    Int J Inj Contr Saf Promot 2020; :1-14Varghese M
  • Modern medicine and surgery is historically very recent, and most interventions that are so commonly done in a hospital now are only 60 to 70 years old. Understanding of emergency care of the injured is more recent; however, for the sake of temporal convenience trauma care has become compartmentalized into phases: first aid, bystander care, prehospital care, emergency care, definitive levels of c…
  • Characterization of Hypoxia-associated Molecular Features to Aid Hypoxia-Targeted Therapy. [Journal Article]
    Nat Metab 2019; 1(4):431-444Ye Y, Hu Q, … Han L
  • Tumor hypoxia is a major contributor to resistance to anti-cancer therapies. Given that the results of hypoxia-targeted therapy trials have been disappointing, a more personalized approach may be needed. Here we characterize multi-OMIC molecular features associated with tumor hypoxia and identify molecular alterations that correlate with both drug-resistant and drug-sensitive responses to anti-ca…
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