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526,685 results
  • Feasibility of Citrate Dialysis in Hyponatremia: A Case Series. [Journal Article]
    Blood Purif. 2020 Jul 08 [Online ahead of print]Redant S, De Bels D, … Honoré PM
  • CONCLUSIONS: The mean serum sodium increase in our series of patients did not exceed the increase of 10-12 mEq/L/day permitted by the guidelines. The excess sodium was absorbed by the filter.In this small series of patients, with adjustment of the sodium concentration of dialysate and reinjection fluid, the use of citrate was found to be safe.
  • Shear stress induced by fluid flow produces improvements in tissue-engineered cartilage. [Journal Article]
    Biofabrication. 2020 Jul 08 [Online ahead of print]Salinas E, Aryaei A, … Athanasiou K
  • Tissue engineering aims to create implantable biomaterials for the repair and regeneration of damaged tissues. In vitro tissue engineering is generally based on static culture, which limits access to nutrients and lacks mechanical signaling. Using shear stress is controversial because in some cases it can lead to cell death while in others it promotes tissue regeneration. To understand how shear …
  • Review on biophysical modelling and simulation studies for transcranial magnetic stimulation. [Journal Article]
    Phys Med Biol. 2020 Jul 08 [Online ahead of print]Gomez-Tames J, Laakso I, Hirata A
  • Transcranial magnetic stimulation (TMS) is a technique for noninvasively stimulating a brain area for therapeutic, rehabilitation treatments and neuroscience research. Despite our understanding of the physical principles and experimental developments pertaining to TMS, it is difficult to identify the exact brain target as the generated electric field exhibits a non-uniform distribution owing to t…
  • Regulatory T Cells Play a Role in a Subset of Idiopathic Preterm Labor/Birth and Adverse Neonatal Outcomes. [Journal Article]
    Cell Rep. 2020 Jul 07; 32(1):107874.Gomez-Lopez N, Arenas-Hernandez M, … Tarca AL
  • Regulatory T cells (Tregs) have been exhaustively investigated during early pregnancy; however, their role later in gestation is poorly understood. Herein, we report that functional Tregs are reduced at the maternal-fetal interface in a subset of women with idiopathic preterm labor/birth, which is accompanied by a concomitant increase in Tc17 cells. In mice, depletion of functional Tregs during l…
  • SOD1 Suppression with Adeno-Associated Virus and MicroRNA in Familial ALS. [Journal Article]
    N Engl J Med. 2020 Jul 09; 383(2):151-158.Mueller C, Berry JD, … Brown RH
  • Two patients with familial amyotrophic lateral sclerosis (ALS) and mutations in the gene encoding superoxide dismutase 1 (SOD1) were treated with a single intrathecal infusion of adeno-associated virus encoding a microRNA targeting SOD1. In Patient 1, SOD1 levels in spinal cord tissue as analyzed on autopsy were lower than corresponding levels in untreated patients with SOD1-mediated ALS and in h…
  • Phase 1-2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS. [Journal Article]
    N Engl J Med. 2020 Jul 09; 383(2):109-119.Miller T, Cudkowicz M, … Ferguson TA
  • CONCLUSIONS: In adults with ALS due to SOD1 mutations, CSF SOD1 concentrations decreased at the highest concentration of tofersen administered intrathecally over a period of 12 weeks. CSF pleocytosis occurred in some participants receiving tofersen. Lumbar puncture-related adverse events were observed in most participants. (Funded by Biogen; number, NCT02623699; EudraCT number, 2015-004098-33.).
  • Lupus erythematosus cell in body fluids: A case report and review of literature. [Journal Article]
    Diagn Cytopathol. 2020 Aug; 48(8):773-777.Ningombam A, Sarkar A, … Chopra A
  • The diagnosis of systemic lupus erythematosus (SLE) has undergone radical change after the development of serological techniques. The in vitro demonstration of lupus erythematosus (LE) cell has less significance for the diagnosis of SLE in the present scenario. Although over the years, the spontaneous in vivo occurrence of LE cell in numerous body fluids as an initial presentation of SLE has been…
  • Sound Propagation and Quantum-Limited Damping in a Two-Dimensional Fermi Gas. [Journal Article]
    Phys Rev Lett. 2020 Jun 19; 124(24):240403.Bohlen M, Sobirey L, … Moritz H
  • Strongly interacting two-dimensional Fermi systems are one of the great remaining challenges in many-body physics due to the interplay of strong local correlations and enhanced long-range fluctuations. Here, we probe the thermodynamic and transport properties of a 2D Fermi gas across the BEC-BCS crossover by studying the propagation and damping of sound modes. We excite particle currents by impri…
  • Surface Tensions between Active Fluids and Solid Interfaces: Bare vs Dressed. [Journal Article]
    Phys Rev Lett. 2020 Jun 19; 124(24):248003.Zakine R, Zhao Y, … van Wijland F
  • We analyze the surface tension exerted at the interface between an active fluid and a solid boundary in terms of tangential forces. Focusing on active systems known to possess an equation of state for the pressure, we show that interfacial forces are of a more complex nature. Using a number of macroscopic setups, we show that the surface tension is a combination of an equation-of-state abiding pa…
  • Nonequilibrium Thermodynamics of Turbulence-Driven Rotors. [Journal Article]
    Phys Rev Lett. 2020 Jun 26; 124(25):254501.Francois N, Xia H, … Shats M
  • We characterize a process of energy extraction via rectification of strongly turbulent flow by using tools of stochastic thermodynamics. We study the dynamics of an asymmetric autonomous rotor that shows biased direction of rotation when placed in a stream. We give experimental evidence that a fluctuation theorem can be used to describe the work injected in the rotor via its coupling with the tur…
  • Statistics of Kinetic Dissipation in the Earth's Magnetosheath: MMS Observations. [Journal Article]
    Phys Rev Lett. 2020 Jun 26; 124(25):255101.Bandyopadhyay R, Matthaeus WH, … Burch JL
  • A familiar problem in space and astrophysical plasmas is to understand how dissipation and heating occurs. These effects are often attributed to the cascade of broadband turbulence which transports energy from large scale reservoirs to small scale kinetic degrees of freedom. When collisions are infrequent, local thermodynamic equilibrium is not established. In this case the final stage of energy …
  • Bursts Characterize Coagulation of Rods in a Quiescent Fluid. [Journal Article]
    Phys Rev Lett. 2020 Jun 26; 124(25):258001.Słomka J, Stocker R
  • Under favorable conditions, microscopic phytoplankton cells dwelling in the oceans can divide rapidly and reach high concentrations, forming blooms that span kilometers and last for weeks. When blooms collapse, dead cells settle and aggregate into "marine snow" particles, resulting in a large and climatically important vertical flux of carbon from the ocean surface to its depth, a process known a…
  • Fungal endophthalmitis: A 20-year experience at a tertiary referral centre. [Journal Article]
    Clin Exp Ophthalmol. 2020 Jul 08 [Online ahead of print]Bhullar GK, Dawkins RCH, … Allen PJ
  • CONCLUSIONS: Our case series provides important insights into fungal endophthalmitis - a high degree of suspicion for fungal endophthalmitis in patients with history of IVDU, and relatively good outlook for vision when Candida is the causative organism. This should allow institutions to implement a standardised management strategy based on evidence. This article is protected by copyright. All rights reserved.
  • Empowering microfluidics by micro-3D printing and solution-based mineral coating. [Journal Article]
    Soft Matter. 2020 Jul 08 [Online ahead of print]Li H, Raza A, … Zhang T
  • Fluid-solid interaction in porous materials is of tremendous importance to earth, space, energy, environment, biological, and medical applications. High-resolution 3D printing enables efficient fabrication of porous microfluidic devices with complicated pore-throat morphology, but lacking desired surface functionality. In this work, we propose a novel approach to additively fabricate functional p…
  • Evaporation of Ar/Kr mixtures on platinum surface: a molecular dynamics study. [Journal Article]
    Phys Chem Chem Phys. 2020 Jul 08 [Online ahead of print]Cai S, Li Q, … Zhang L
  • Evaporation is a typical heat and mass transfer process, which is important in both nature and industry. Here, the evaporation of five fluid samples (pure Ar, pure Kr and Ar/Kr mixtures with molar ratio Ar : Kr = 1 : 3, Ar : Kr = 1 : 1 and Ar : Kr = 3 : 1) on Pt surface was investigated using molecular dynamics simulations. Colligative properties of the mixtures led to the melting of the Ar/Kr mi…
  • Nanomaterial based drug delivery systems for the treatment of neurodegenerative diseases. [Review]
    Biomater Sci. 2020 Jul 08 [Online ahead of print]Masoudi Asil S, Ahlawat J, … Narayan M
  • With an aging population that has been increasing in recent years, the need for the development of therapeutic approaches for treatment of neurodegenerative disorders (ND) has increased. ND, which are characterized by the progressive loss of the structure or function of neurons, are often associated with neuronal death. In spite of screening numerous drugs, currently there is no specific treatmen…
  • Novel trends in the thermo-chemical recycling of plastics from WEEE containing brominated flame retardants. [Review]
    Environ Sci Pollut Res Int. 2020 Jul 07 [Online ahead of print]Charitopoulou MA, Kalogiannis KG, … Achilias DS
  • The amount of plastics from waste electric and electronic equipment (WEEE) has enormously increased nowadays, due to the rapid expansion and consumption of electronic devices and their short lifespan. This, in combination with their non-biodegradability, led to the need to explore environmentally friendly solutions for their safe disposal. One main obstacle when recycling plastics from WEEE is th…
  • Rab Proteins: Insights into Intracellular Trafficking in Endometrium. [Review]
    Reprod Sci. 2020 Jul 07 [Online ahead of print]Leiva NL, Nolly MB, … Damiani MT
  • Rab proteins belong to the Ras superfamily of small monomeric GTPases. These G proteins are the main controllers of vesicular transport in every tissue, among them, the endometrium. They are in charge of to the functional subcellular compartmentalization and cargo transport between organelles and the plasma membrane. In turn, intracellular trafficking contributes to endometrial changes during the…
  • In vitro activity of isavuconazole against clinically isolated yeasts from Chile. [Journal Article]
    Braz J Microbiol. 2020 Jul 07 [Online ahead of print]Álvarez Duarte E, Salas V
  • Isavuconazole is the last antifungal agent approved by the FDA and available for treatment of fungal infections. In the present study, the in vitro activity of isavuconazole against several yeasts was investigated. Two hundred forty-six isolates were included: 64 Candida albicans, 53 Candida parapsilosis sensu stricto, 48 Cryptococcus neoformans species complex, 27 C. glabrata sensu stricto, 17 C…
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