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4,392 results
  • StatPearls: Fluticasone [BOOK]
  • BOOKStatPearls Publishing: Treasure Island (FL)
  • Remien Kailey K Campbell University Bowman Andy A Campbell University
  • Fluticasone is corticosteroid given via oral, nasal, or topical routes. The route of administration depends on the patient’s diagnoses. Oral fluticasone is FDA-approved to treat asthma and has an off…
  • Inhaled corticosteroids in children with persistent asthma: effects of different drugs and delivery devices on growth. [Review]
  • CDCochrane Database Syst Rev 2019 Jun 10; 6:CD010126
  • Axelsson I, Naumburg E, … Zhang L
  • CONCLUSIONS: This review suggests that the drug molecule and delivery device may impact the effect size of ICS on growth in children with persistent asthma. Fluticasone at an equivalent dose seems to inhibit growth less than beclomethasone and budesonide. Easyhaler is likely to have less adverse effect on growth than Turbuhaler when used for delivery of budesonide. However, the evidence from this systematic review of head-to-head trials is not certain enough to inform the selection of inhaled corticosteroid or inhalation device for the treatment of children with persistent asthma. Further studies are needed, and pragmatic trials and real-life observational studies seem more attractive and feasible.
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