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(fondaparinux)
1,889 results
  • From multi-target anticoagulants to DOACs, and intrinsic coagulation factor inhibitors. [Review]
    Blood Rev 2019; :100615Lin L, Zhao L, … Zhao J
  • From the 1940s to 1990s, heparin and warfarin have been the main anticoagulants for the prevention and treatment of thrombotic events. Since then, LMWHs and fondaparinux proved effective in clinical trials, with better pharmacokinetic profiles and no monitoring requirements. Developed in the early 21st century, DOACs have comparable efficacy to LMWHs, but increase bleeding risk, as the anticoagul…
  • Inpatient management strategies in a severe case of heparin-induced thrombocytopenia. [Journal Article]
    Transfus Apher Sci 2019; 58(4):525-528Shmookler AD, Arays R, McCarthy P
  • We present important laboratory testing and clinical management strategies used to safely discharge home a 69-year old woman with heparin-induced thrombocytopenia (HIT) from the hospital. She was admitted for a coronary artery bypass graft procedure for which she was anticoagulated with heparin. Shortly after the procedure she developed thrombocytopenia and was diagnosed with HIT using the 4Ts sc…
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