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Unbound Medicine.
(fusospirochetosis)
1,214 results
  • StatPearls: Necrotizing Periodontitis [BOOK]
    . StatPearls Publishing: Treasure Island (FL) Gasner Noah S. NS University of Toronto Schure Ryan S. RS Faculty of Dentistry, University of Toronto BOOK
  • Necrotizing periodontitis (NP), previously referred to as necrotizing ulcerative periodontitis, is a specific subset of necrotizing periodontal diseases (NPD). In general, NP is a reactive, destructive inflammatory process in response to bacterial inflammation, and represents the most severe form of the biofilm-related diseases.[1] Although rare in modern industrialized society, this disease proc…
  • Oral spirochetes: Pathogenic mechanisms in periodontal disease. [Review]
    Microb Pathog. 2020 Jul; 144:104193.Yousefi L, Leylabadlo HE, … Kafil HS
  • Periodontitis is an infectious inflammatory disease resulting from infection of biofilm forming bacteria. Several bacterial factors regulate inflammatory response and cause to tissue damage and loss of connection between gingival and tooth. Since bacterial virulence factors and also host immune responses have role, understanding of periodontal disease is complex, in overall we can say that in thi…
  • GINGIVAL ULCERATIONS IN A PATIENT WITH ACUTE MYELOID LEUKEMIA: A case report and literature review. [Case Reports]
    Acta Clin Croat. 2019 Sep; 58(3):556-560.Vučićević Boras V, Vidović Juras D, … Mikulić M
  • A 40-year-old female patient was admitted to the Department of Oral Medicine due to oral ulcerations. Oral ulcerations were present on vestibular mucosa above teeth 21, 22, 25 and 26 and were 1 cm in diameter, and also around teeth 45 and 46. The patient had prolonged neutropenia due to therapy-related myelodysplastic syndrome that progressed to therapy-related acute myeloid leukemia. Initially, …
  • Immunopathogenesis of canine chronic ulcerative stomatitis. [Journal Article]
    PLoS One. 2020; 15(1):e0227386.Anderson JG, Kol A, … Murphy BG
  • Canine Chronic Ulcerative Stomatitis is a spontaneously occurring inflammatory disease of the oral mucosa. An immune-mediated pathogenesis is suspected though not yet proven. We have recently reported on the clinical and histologic features, and identification of select leukocyte cell populations within the lesion. A clinical and histologic similarity to oral lichen planus of people was proposed.…
  • Oral histoplasmosis masquerading as acute necrotizing ulcerative gingivitis: A rare case report. [Case Reports]
    Int J Health Sci (Qassim). 2019 Sep-Oct; 13(5):37-40.Khetarpal S, Mhapsekar T, … Parihar A
  • Histoplasmosis also called as "Darling's Disease" is a community-acquired primary pulmonary disease caused by inhalation of dust containing spores of soil-dwelling dimorphic fungi, Histoplasma capsulatum. Presentation of fungi in the oral cavity is usually rare and is generally associated with an immunocompromised state. Here, we present a rare case of histoplasmosis in an immunocompetent patient…
  • Clinical treatment of necrotizing ulcerative gingivitis: a case report with 10-year follow-up. [Case Reports]
    Gen Dent. 2019 May-Jun; 67(3):62-65.Martos J, Ahn Pinto KV, … César Neto JB
  • The aim of this case report is to describe the diagnosis and treatment of a patient with necrotizing ulcerative gingivitis. An 18-year-old man with no systemic problems reported with chief complaints of gingival bleeding during toothbrushing and spontaneous pain. Clinical examination revealed significant plaque accumulation on the surfaces of all teeth as well as papillary necrosis involving main…
  • Diagnosis of a case of ligneous gingivitis in a patient with moderate plasminogen deficiency. [Case Reports]
    J Stomatol Oral Maxillofac Surg. 2019 Jun; 120(3):270-272.Malthiery E, Torres JH, … Fauroux MA
  • Plasminogen deficiency is a rare congenital condition that leads to pseudomembraneous lesions, such as ligneous conjunctivitis and ligneous gingivitis. Because of its rarity, ligneous gingivitis is not a pathology one may easily suspect from its clinical symptoms. We report the case of a 35-year-old Caucasian woman who experienced gum masses with white spots, but no pain. Based on the clinical pi…
  • Chronic ulcerative stomatitis: A comprehensive review and proposal for diagnostic criteria. [Journal Article]
    Oral Dis. 2019 Sep; 25(6):1465-1491.Azzi L, Cerati M, … Olszewska M
  • Chronic ulcerative stomatitis (CUS) is an immune-mediated disorder characterized by oral erosions and ulcers usually refractory to conventional treatments. The disease often involves middle-aged and older women with painful lesions sometimes resembling those of erosive oral lichen planus (OLP). The most affected sites are the buccal mucosa, the gingiva and the tongue, but the skin is involved in …
  • Seventeen New Cases of Chronic Ulcerative Stomatitis with Literature Review. [Review]
    Head Neck Pathol. 2019 Sep; 13(3):386-396.Reddy R, Fitzpatrick SG, … Islam MN
  • Chronic ulcerative stomatitis (CUS) is a poorly understood disease with clinical and histologic overlap with lichen planus (LP). Unlike classic LP, direct immunofluorescence (DIF) studies in cases of CUS exhibit a granular pattern of IgG in nuclei of basal and parabasal cells. This study assesses the demographic, clinical, histologic, and DIF features of CUS. It is important to differentiate CUS …
  • Chronic ulcerative stomatitis: Case series of an under-recognized entity. [Case Reports]
    J Cutan Pathol. 2018 Dec; 45(12):927-932.Ko EM, Danciu TE, … Chan MP
  • Chronic ulcerative stomatitis (CUS) is a mucocutaneous condition characterized by chronic relapsing and remitting oral ulcers and erosions. This condition remains under-recognized among dermatopathologists, possibly because of common misdiagnosis as oral erosive lichen planus (LP). We report five cases of CUS in order to raise awareness of this uncommon condition. All patients presented with desq…
  • Identification of bacteria present in ulcerative stomatitis lesions of captive sea turtles Chelonia mydas. [Journal Article]
    Vet Res Commun. 2018 Sep; 42(3):251-254.Vega-Manriquez DX, Dávila-Arrellano RP, … Muñoz-Tenería FA
  • Anthropogenic activities, predation, and diseases have contributed to a decrease in the sea turtle population in recent years. Ulcerative stomatitis is a condition that occurs in both wild and captive populations. The etiology of this condition is associated with bacteria such as E. coli, Citrobacter diversus, Klebsiella spp., Pseudomonas spp., Flavobacter calcoaceticus, Staphylococcus spp., and …
  • Antibiotic Prescribing for Oro-Facial Infections in the Paediatric Outpatient: A Review. [Review]
    Antibiotics (Basel). 2018 Apr 25; 7(2)Dar-Odeh N, Fadel HT, … Abu-Hammad OA
  • There are many reports on the complications associated with antibiotics abuse during the treatment of paediatric patients, particularly those related to antimicrobial resistance. The dental profession is no exception; there is growing evidence that dental practitioners are misusing antibiotics in the treatment of their paediatric patients. This review is directed to dental practitioners who provi…
  • Necrotizing Ulcerative Gingivitis. [Case Reports]
    Contemp Clin Dent. 2017 Jul-Sep; 8(3):496-500.Malek R, Gharibi A, … Kissa J
  • Necrotizing ulcerative gingivitis (NUG) is a typical form of periodontal diseases. It has an acute clinical presentation with the distinctive characteristics of rapid onset of interdental gingival necrosis, gingival pain, bleeding, and halitosis. Systemic symptoms such as lymphadenopathy and malaise could be also found. There are various predisposing factors such as stress, nutritional deficienci…
  • Clinicopathologic significance of in vivo antinuclear autoantibodies in oral mucosal biopsies. [Journal Article]
    Oral Surg Oral Med Oral Pathol Oral Radiol. 2017 Nov; 124(5):475-482.Alshagroud R, Neiders M, … Suresh L
  • CONCLUSIONS: We found similar prevalence of ANA staining with direct immunofluorescence in oral epithelial biopsy specimens as reported for those of skin. In vivo ANA in the oral epithelium may indicate the presence of an immune-mediated disease. Patients who show ANA deposits in oral mucosal biopsy specimens should be investigated for systemic connective tissue disease as well as for chronic ulcerative stomatitis.
  • Unexpected Acute Necrotizing Ulcerative Gingivitis in a Well-controlled HIV-infected Case. [Case Reports]
    Intern Med. 2017 Aug 15; 56(16):2223-2227.Kato H, Imamura A
  • We herein report the case of a 41-year-old Japanese man with well-controlled HIV who presented with diagnostically difficult acute necrotizing ulcerative gingivitis (ANUG). After diet-induced weight loss, he developed oral pain and disturbance of mouth opening, and was admitted to our hospital. Based on preconceptions of HIV-associated diseases, fluconazole was initiated for candidiasis. However,…
  • Necrotising Ulcerative Gingivitis: A Literature Review. [Historical Article]
    Oral Health Prev Dent. 2017; 15(4):321-327.Dufty J, Gkranias N, Donos N
  • CONCLUSIONS: Although there is low prevalence of NUG, its importance should not be underestimated as one of the most severe responses to the oral biofilm. Risk factors must be investigated and addressed. Treatment should consist of gentle superficial debridement, oral hygiene instruction and prescription of mouthwash and antibiotics in severe cases.
  • [Necrotizing ulcerative diseases in military population]. [Case Reports]
    Refuat Hapeh Vehashinayim (1993). 2017 04; 34(2):73-78, 91.Averbuch Zehavi E, Arbel Y, … Via S
  • Necrotizing ulcerative diseases were prevalent in military personnel throughout history. Nowadays, its prevalence declined substantially in industrialized countries. Studies among immunocompromised patients suggest it is still a reason for concern among this population. We present two cases diagnosed and treated at our department. It seems that necrotizing ulcerative diseases are still a relevant…
  • Clinical and Histopathologic Characterization of Canine Chronic Ulcerative Stomatitis. [Journal Article]
    Vet Pathol. 2017 05; 54(3):511-519.Anderson JG, Peralta S, … Murphy B
  • Canine chronic ulcerative stomatitis, also known as chronic ulcerative paradental stomatitis, is a painful condition of the oral cavity. The purpose of this study was to determine if there are commonalities in clinical and radiographic features among patients, whether the histopathologic evaluation might inform the pathogenesis, and whether the condition appears similar to human oral mucosal dise…
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