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59,218 results
  • The Relationships Between Ataxia and Cognition in Spinocerebellar Ataxia Type 2. [Journal Article]
    Cerebellum 2019Gigante AF, Lelli G, … Defazio G
  • The clinical spectrum of spinocerebellar ataxia type 2 includes motor manifestations and cognitive disturbances in executive functions, memory, and visuoconstructive skills. The relationships between severity of motor disturbances and altered cognition are poorly known. In this study, we assessed patients with spinocerebellar ataxia type 2 and age- and sex-matched healthy control subjects by a te…
  • POLR3A-related spastic ataxia: new mutations and a look into the phenotype. [Journal Article]
    J Neurol 2019Infante J, Serrano-Cárdenas KM, … Matilla-Dueñas A
  • Adolescent-onset spastic ataxia is a proposed novel phenotype in compound heterozygous carriers of an intronic mutation (c.1909 + 22G > A) in the POLR3A gene. Here, we present ten new cases of POLR3A-related spastic ataxia and discuss the genetic, clinical and imaging findings. Patients belonged to six pedigrees with hereditary spastic paraplegia or cerebellar ataxia of unknown origin. All affect…
  • Spontaneous resolution of chronic subdural hematoma: Does only the size matter? [Case Reports]
    Surg Neurol Int 2019; 10:194Junior MGP, Pessoa BL, … Leite MAA
  • CONCLUSIONS: In this report, we discuss the spontaneous resolution of a large CSDH in elderly patients, without surgical intervention. Gradually, several successful nonsurgical therapies for the treatment of these hematomas are reported, although further studies are essential to establish the role of these nonsurgical treatments of CSDHs.
  • HIV-Associated Vacuolar Myelopathy and HIV-Associated Dementia as the Initial Manifestation of HIV/AIDS. [Case Reports]
    Case Rep Infect Dis 2019; 2019:3842425Wuliji N, Mandell MJ, … Merando A
  • HIV-associated vacuolar myelopathy (HIV-VM) is the most common cause of spinal disease in HIV/AIDS. HIV-VM causes progressive spastic paraparesis, sensory ataxia, and autonomic dysfunction. It is a progressive myelopathy that shares features with subacute combined degeneration seen in vitamin B12 deficiency as well as other neurological diseases and can occur synchronously with HIV-associated dem…
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