Download the Free Prime PubMed App to your smartphone or tablet.

Available for iPhone or iPad:

Unbound PubMed app for iOS iPhone iPadAlso Available:
Unbound MEDLINE
Unbound PubMed app for Android

Available for Mac and Windows Desktops and laptops:

Unbound PubMed app for WindowsUnbound PubMed app for MAC OS Yosemite Macbook Air pro
(gatekeeper)
2,952 results
  • Inter-organ communication: a gatekeeper for metabolic health. [Review]
    EMBO Rep 2019; :e47903Castillo-Armengol J, Fajas L, Lopez-Mejia IC
  • Multidirectional interactions between metabolic organs in the periphery and the central nervous system have evolved concomitantly with multicellular organisms to maintain whole-body energy homeostasis and ensure the organism's adaptation to external cues. These interactions are altered in pathological conditions such as obesity and type 2 diabetes. Bioactive peptides and proteins, such as hormone…
  • [The future problems of general practice in Germany: current trends and necessary measures]. [Review]
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2019van den Bussche H
  • In Germany there is a threat of a shortage of junior general practitioners (GPs). One third of currently employed GPs are 60 years and older. Every year, 1700 GPs leave the profession, while only about 1350 new GP-specialist approvals are issued. The Advisory Council on the Assessment of Developments in the Health Care Sector estimates that there will be around 20,000 unmet replacement needs by 2…
  • Ancestral reconstruction reveals mechanisms of ERK regulatory evolution. [Journal Article]
    Elife 2019; 8Sang D, Pinglay S, … Holt LJ
  • Protein kinases are crucial to coordinate cellular decisions and therefore their activities are strictly regulated. Previously we used ancestral reconstruction to determine how CMGC group kinase specificity evolved (Howard et al., 2014). In the present study, we reconstructed ancestral kinases to study the evolution of regulation, from the inferred ancestor of CDKs and MAPKs, to modern ERKs. Kina…
New Search Next