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(germ cell aplasia germinal cell aplasia)
59 results
  • StatPearls: Sertoli-Cell-Only Syndrome [BOOK]
    StatPearls Publishing: Treasure Island (FL) Ramphul Kamleshun K Shanghai Jiao Tong University Zulfiqar Hassam H Rawalpindi Medical University Mejias Stephanie G. SG UNIBE University BOOK
  • Sertoli cell-only syndrome (SCO) is also known as Del Castillo syndrome and germ cell aplasia. Sertoli cells are found in the convoluted seminiferous tubules and form part of the blood-testis barrier in males. They also play an important role in spermatogenesis which is sperm production. The cells respond to a hormone called follicle-stimulating hormone (FSH) that is released by the hypothalamus.…
  • Immunohistochemical measurement and expression of Mcl-1 in infertile testes. [Journal Article]
    Front Med 2015; 9(3):361-7Hegazy R, Hegazy A, … Salem E
  • The diagnosis of azoospermia represents a major challenge to andrologists as this condition may occur despite normal spermatogenesis and genital tracts. Myeloid cell leukemia-1 (Mcl-1) is a member of the Bcl-2 family of proteins involved in regulation of apoptosis in various cell types. This study aimed to investigate the immunohistochemical expression of Mcl-1 in testicular biopsies of subjects …
  • Endotext: Primary Testicular Failure [BOOK]
    MDText.com, Inc.: South Dartmouth (MA)Feingold KR, Anawalt B, … Wilson DPBehre HM, Bergmann M, … Tüttelmann FBOOK
  • Primary testicular failure may result in endocrine failure, leading to testosterone deficiency or exocrine failure causing impaired spermatogenesis and subsequently male infertility. While some aspects of primary testicular failure are described in detail in separate chapters of Endotext.com, this chapter focuses on congenital or acquired anorchia, Leydig cell hypoplasia, and spermatogenic failur…
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