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Unbound Medicine.
(germicidal)
930 results
  • Far-UVC light (222 nm) efficiently and safely inactivates airborne human coronaviruses. [Journal Article]
    Sci Rep. 2020 06 24; 10(1):10285.Buonanno M, Welch D, … Brenner DJ
  • A direct approach to limit airborne viral transmissions is to inactivate them within a short time of their production. Germicidal ultraviolet light, typically at 254 nm, is effective in this context but, used directly, can be a health hazard to skin and eyes. By contrast, far-UVC light (207-222 nm) efficiently kills pathogens potentially without harm to exposed human tissues. We previously demons…
  • Optically activated and interrogated plasmonic hydrogels for applications in wound healing. [Journal Article]
    J Biophotonics. 2020 Jun 15 [Online ahead of print]Milanesi A, Magni G, … Pini R
  • We disclose the use of hybrid materials featuring Au/Ag core/shell nanorods in porous chitosan/polyvinyl alcohol scaffolds for applications in tissue engineering and wound healing. The combination of Au and Ag in a single construct provides synergistic opportunities for optical activation of functions as near infrared laser tissue bonding, and remote interrogation to return parameters of prognost…
  • Harmless Effects of Sterilizing 222-nm far-UV Radiation on Mouse Skin and Eye Tissues. [Journal Article]
    Photochem Photobiol. 2020 Jun 11 [Online ahead of print]Cadet J
  • There is growing interest in using ultraviolet (UV) radiation for bactericidal and viral decontamination of air, surfaces and foods, a trend that is reinforced during the Covid-19 pandemic. For almost a century and a half, UVC and UVB radiations have been used extensively for non-thermal sterilization against various microbial pathogens by developing so-called ultraviolet germicidal irradiation (…
  • Evidence for decontamination of single-use filtering facepiece respirators. [Review]
    J Hosp Infect. 2020 May 27 [Online ahead of print]Polkinghorne A, Branley J
  • Single-use filtering face respirators (FFRs) are critical pieces of personal protective equipment for healthcare workers treating patients with suspected upper respiratory tract pathogens. Experiences during pandemics in the 2000s, as well as the ongoing COVID-19 pandemic caused by the SARS-2-CoV2, have highlighted concerns over the pressures that sustained respiratory virus pandemics may have on…
  • Improper use of germicidal range ultraviolet lamp for household disinfection leading to phototoxicity in COVID-19 suspects. [Journal Article]
    Cornea. 2020 Apr 29 [Online ahead of print]Leung KCP, Ko TCS
  • CONCLUSIONS: Although SARS-CoV-2 is structurally akin to SARS-CoV-1 and MERS-CoV, and previous studies demonstrated high levels of inactivation of beta-coronavirus with germicidal-range UV, evidence for its efficacy to inactivate SARS-CoV-2 is lacking. This case report serves to emphasize the potential consequences of phototoxicity from improper use of UV germicidal lamps for household disinfection as well as to highlight the fact that UV germicidal lamps currently have no established role in household disinfection of SARS-CoV-2.
  • Covid-19 and the N95 respirator shortage: Closing the gap. [Journal Article]
    Infect Control Hosp Epidemiol. 2020 Apr 13 [Online ahead of print]Nogee D, Tomassoni AJ
  • Due to extreme shortages of personal protective equipment caused by the COVID-19 pandemic, many healthcare workers will be forced to recycle protective masks intended for disposal after a single use. We propose investigating the use of ultraviolet germicidal irradiation to sterilize masks of SARS-CoV-2 for safer reuse.
  • 222-nm UVC inactivates a wide spectrum of microbial pathogens. [Journal Article]
    J Hosp Infect. 2020 Mar 31 [Online ahead of print]Narita K, Asano K, … Nakane A
  • CONCLUSIONS: The 222-nm UVC is able to inactivate a wide spectrum of microbial pathogens. In comparison with the conventional 254-nm UVC, the germicidal effect of 222-nm UVC to the fungal hyphae and spores is low, but the 222-nm UVC exhibits strong germicidal effect to the bacterial endospores.
  • [The evaluation of optical radiation hazards: methods, case studies and critical aspects]. [Journal Article]
    G Ital Med Lav Ergon. 2019 12; 41(4):274-279.Pinto I, Bogi A, … Stacchini N
  • Purpose. Currents methods for the evaluation and control of optical radiation hazards at workplaces are presented. Methods. Safe exposure criteria that may be readily applied to practical situations are discussed. Hazard evaluation techniques are discussed for a number of intense optical radiation sources. Examples include arc welding, germicidal lamps in medical and laboratories activities, meta…
  • The efficacy of vacuum-ultraviolet light disinfection of some common environmental pathogens. [Journal Article]
    BMC Infect Dis. 2020 Feb 11; 20(1):127.Szeto W, Yam WC, … Leung DYC
  • CONCLUSIONS: Following the criteria that valid germicidal results can be reflected with 3-log10 inactivation for bacteria, 4-log10 inactivation for viruses and 5-log10 inactivation for MTB, most of the bacteria required ≤10 min of VUV treatment, 20 min for the influenza viruses while MTB needed about 30 min VUV treatment. This indicated that VUV light is an effective approach against different environmental microorganisms.
  • Unique Thia-Baeyer-Villiger-Type Oxidation of Dibenzothiophene Sulfoxides Derivatives. [Journal Article]
    Chem Asian J. 2020 Feb 17; 15(4):511-517.Shi W, Zhou X, … Markó IE
  • The present research has demonstrated that selective C-S bond cleavages of dibenzothiophene and its derivatives are feasible by thia-Baeyer-Villiger type oxidation, i. e. the oxygen insertion process within a sulfoxide-carbon linkage, in the presence of porphyrin iron (III) and by ultraviolet irradiation originating from sunlight, high pressure Hg-lamp or residentially germicidal ultraviolet lamp…
  • Directed evolution by UV-C treatment of Bacillus cereus spores. [Journal Article]
    Int J Food Microbiol. 2020 Mar 16; 317:108424.Begyn K, Kim TD, … Devlieghere F
  • Bacterial endospores are exposed to a broad variety of sublethal and lethal stresses in the food production chain. Generally, these stresses will not completely eliminate the existing spore populations, and thus constitute a selection pressure on the spores. One stress that is frequently used in the food production chains to disinfect (food) contact surfaces is UV-C. At a wavelength of 254 nm, UV…
  • Preventing Transmission of Mycobacterium Tuberculosis-A Refocused Approach. [Review]
    Clin Chest Med. 2019 12; 40(4):857-869.Nardell EA
  • Traditional tuberculosis (TB) infection control focuses on the known patient with TB, usually on appropriate treatment. A refocused, intensified TB infection control approach is presented. Combined with active case finding and rapid molecular diagnostics, an approach called FAST is described as a convenient way to call attention to the untreated patient. Natural ventilation is the mainstay of air…
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