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358,767 results
  • StatPearls: Muscarinic Agonists [BOOK]
    StatPearls Publishing: Treasure Island (FL) Bui Toai T SGMC Duong Hieu H BOOK
  • Muscarinic receptors are primarily on the postsynaptic cell membrane of smooth muscle, cardiac muscle, and exocrine gland cells. Muscarinic receptors are activated by acetylcholine and increase the activity of the parasympathetic nervous system. Muscarinic agonist mimics the action of acetylcholine on muscarinic receptors and causes cardiac slowing, contraction of smooth muscles (intestinal tract…
  • Model to Link Cell Shape and Polarity with Organogenesis. [Journal Article]
    iScience 2020; 23(2):100830Nielsen BF, Nissen SB, … Trusina A
  • How do flat sheets of cells form gut and neural tubes? Across systems, several mechanisms are at play: cells wedge, form actomyosin cables, or intercalate. As a result, the cell sheet bends, and the tube elongates. It is unclear to what extent each mechanism can drive tube formation on its own. To address this question, we computationally probe if one mechanism, either cell wedging or intercalati…
  • Enteric Type Bartholin Gland Adenocarcinoma: An Unusual Variant of a Rare Neoplasm. [Journal Article]
    Int J Gynecol Pathol 2020Robinson H, Karpe M, … O'Donnell RL
  • Vulval cancer is rare. With Bartholin gland carcinomas representing <5% of all vulval carcinomas they present both diagnostic and management challenges. There are a small number of cases in the literature describing Bartholin gland carcinomas with unusual histology which necessitates the need to explore the possibility of metastases from elsewhere. We present a case of a 55-yr-old woman presentin…
  • Establishment of a Severe Dry Eye Model Using Complete Dacryoadenectomy in Rabbits. [Journal Article]
    J Vis Exp 2020; (155)Honkanen RA, Huang L, … Rigas B
  • Dry eye disease (DED) is a complex disease with multiple etiologies and variable symptoms, having ocular surface inflammation as its key pathophysiologic step. Despite advances in our understanding of DED, significant knowledge gaps remain. Advances are limited in part due to the lack of informative animal models. The authors recently reported on a method of DED induced by injecting all orbital l…
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