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1,009,830 results
  • Extracellular Histones Induced Eryptotic Death in Human Erythrocytes. [Journal Article]
  • CPCell Physiol Biochem 2019; 53(1):229-241
  • Yeung KW, Lau PM, … Kong SK
  • CONCLUSIONS: EHs act as a DAMP agent in the human RBCs that induces eryptosis. The cytotoxic effect is rapid as the hallmarks of eryptosis such as cell shrinkage, surface PS exposure, [Ca2+]i rise, ROS production and caspase-3 activation can be seen 3 h after treatment in a dose-dependent manner. The EHs' cytotoxic effects could be blocked by heparin and the Ab against TLR2.
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