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54,530 results
  • Skin infections in Australian Aboriginal children: a narrative review. [Review]
    Med J Aust 2019Davidson L, Knight J, Bowen AC
  • Impetigo, scabies, cellulitis and abscesses are common in Australian Aboriginal children. These conditions adversely affect wellbeing and are associated with serious long term sequelae, including invasive infection and post-infectious complications, such as acute post-streptococcal glomerulonephritis and acute rheumatic fever, which occurs at the highest documented rates in the world in remote Ab…
  • TAFRO syndrome as a cause of glomerular microangiopathy: a case report and literature review. [Journal Article]
    BMC Nephrol 2019; 20(1):375Nagayama Y, Yamano M, … Matsui K
  • CONCLUSIONS: We reviewed our case and other 10 previous reports about renal biopsy findings in TAFRO syndrome and found that glomerular microangiopathy was a common finding. IL-6-VEGF-axis-induced glomerular microangiopathy may play a crucial role in developing acute kidney injury in TAFRO syndrome and the anti-IL-6 receptor antibody therapy may be useful for TAFRO syndrome refractory to glucocorticoids. About the pathophysiology of VEGF in TAFRO syndrome, VEGF balance in the glomerulus and perhaps in the peritubular capillary system as well may be critical. Further investigation is needed.
  • The Role of MicroRNAs in Selected Forms of Glomerulonephritis. [Review]
    Int J Mol Sci 2019; 20(20)Nalewajska M, Gurazda K, … Dziedziejko V
  • Glomerulonephritis (GN) represents a collection of kidney diseases characterized by inflammation within the renal glomeruli and small blood vessels. The lesions that occur in other nephron structures mainly result from the harmful effects of proteinuria. In recent years, an emphasis has been placed on gaining a better insight into the pathogenesis and pathophysiology of GN in order to facilitate …
  • Complement Inhibitors in Clinical Trials for Glomerular Diseases. [Review]
    Front Immunol 2019; 10:2166Zipfel PF, Wiech T, … Skerka C
  • Defective complement action is a cause of several human glomerular diseases including atypical hemolytic uremic syndrome (aHUS), anti-neutrophil cytoplasmic antibody mediated vasculitis (ANCA), C3 glomerulopathy, IgA nephropathy, immune complex membranoproliferative glomerulonephritis, ischemic reperfusion injury, lupus nephritis, membranous nephropathy, and chronic transplant mediated glomerulop…
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