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Unbound Medicine.
(glucokinetic)
2 results
  • Effects of long-term 4-aminopyridine therapy on glucose tolerance and glucokinetics in patients with spinal cord injury. [Clinical Trial]
    Pharmacotherapy. 2007 Jun; 27(6):789-92.Segal JL, Thompson JF, Tayek JA
  • CONCLUSIONS: The long-term administration of an oral, immediate-release formulation of 4-aminopyridine to patients with longstanding spinal cord injury was associated with readily discernible, potentially clinically significant improvements in glucose tolerance. Because impaired glucose tolerance is a common finding in patients with spinal cord injury, more research, including randomized controlled trials with large study populations, is warranted on this potential treatment.
  • Atropine: effects on glucose metabolism. [Journal Article]
    Aviat Space Environ Med. 1990 May; 61(5):424-9.Durkot M, Martinez O, … Hubbard R
  • We have employed the primed constant infusion technique to investigate the metabolic effects of the organophosphate antidote, atropine, on glucose homeostasis in rats. This method utilizes the radioisotopes 6-3H-glucose to measure production and uptake and U-14C-glucose to measure oxidation. Our data indicate that glucose production significantly (p less than 0.05) increased (24.0 +/- 2.0 vs. 30.…
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