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1,396 results
  • PLAID syndrome: Characteristic presentation and a novel therapeutic option. [Case Reports]
    Pediatr Dermatol 2019Shea J, Huynh T, … Chamlin S
  • PLCG2-associated antibody deficiency and immune dysregulation (PLAID) is an autosomal dominant inherited disease caused by genomic deletion in PLCG2 and is characterized by cold urticaria, humoral immune deficiency, cutaneous granulomas, and autoimmune disease. The patient described in this case had a typical presentation for a PLAID phenocopy and experienced intense pruritus, a common complicati…
  • Management Strategies Of Palmar Hyperhidrosis: Challenges And Solutions. [Journal Article]
    Clin Cosmet Investig Dermatol 2019; 12:733-744Gregoriou S, Sidiropoulou P, … Rigopoulos D
  • Palmar hyperhidrosis is a potentially disabling condition for which management remains a therapeutic challenge. Given the significant impact on quality of life, various treatment options are available, ranging from topical agents and medical devices to systemic therapies and surgical interventions. Nonsurgical approaches, i.e. topical antiperspirants, botulinum toxin injections, iontophoresis, an…
  • Anticholinergic medications for reducing drooling in children with developmental disability. [Journal Article]
    Dev Med Child Neurol 2019Reid SM, Westbury C, … Reddihough DS
  • CONCLUSIONS: Benzhexol, glycopyrrolate, and scopolamine reduce drooling, but improvement is offset by adverse side effects. Overall, glycopyrrolate performs best.In drooling, glycopyrrolate produced the greatest improvement with fewer side effects compared with benzhexol and scopolamine. Poor head control and poor oromotor function were associated with poor response. Medication side effects were common and often led to treatment discontinuation. Behavioural issues instigated cessation of benzhexol more often in males than females.
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