- CDKL5 deficiency disorder: Relationship between genotype, epilepsy, cortical visual impairment, and development. [Journal Article]
- EEpilepsia 2019 Jul 16
- CONCLUSIONS: The most common seizure types in CDD are epileptic spasms (often without hypsarrhythmia) and tonic seizures that may cluster together. CVI is a common feature in CDD and is correlated with achieving fewer milestones.
- Plasmid profiling and incompatibility grouping of multidrug resistant Salmonella enterica serovar Typhi isolates in Nairobi, Kenya. [Journal Article]
- BRBMC Res Notes 2019 Jul 16; 12(1):422
- Plasmids harbour antibiotic resistance genes which contribute to the emergence of multidrug resistant pathogens. We detected the presence of plasmids in multidrug resistant Salmonella enterica serova…
Plasmids harbour antibiotic resistance genes which contribute to the emergence of multidrug resistant pathogens. We detected the presence of plasmids in multidrug resistant Salmonella enterica serovar Typhi (S. Typhi) isolates from our previous study and consequently determined their incompatibility groups and possibility of conjugation transmission. Plasmids were extracted from 98 multidrug resistant S. Typhi isolates based on alkaline lysis technique. Plasmid incompatibility grouping was established by PCR replicon typing using 18 pairs of primers to amplify FIA, FIB, FIC, HI1, HI2, I1-Iγ, L/M, N, P, W, T, A/C, K, B/O, X, Y, F and FIIA replicons. Antibiotic resistance phenotypes were conjugally transferred from S. Typhi isolates with plasmids to Escherichia coli K12F strain devoid of plasmids.
- A Study on the Association of Psoriasis with Metabolic Disorders. [Journal Article]
- JAJ Assoc Physicians India 2019; 67(4):52-54
- CONCLUSIONS: The blood pressure, sr. triglycerides, sr. high density lipids, fasting blood sugar were significant in cases as compared to controls satisfying the criteria of Adult Panel Treatment III (ATP III) of Metabolic Disorders.
- Human errors in manual techniques for ABO/D grouping are associated with potentially lethal outcomes. [Journal Article]
- TMTransfus Med 2019 Jul 15
- CONCLUSIONS: Where manual testing cannot be avoided, results should be confirmed using automated techniques as soon as possible, and a back-up process should be available 24/7. SHOT data confirm that manual interventions are prone to human error, especially in transcription and interpretation, and demonstrate a continuing need for appropriate serological knowledge and understanding by transfusion laboratory staff to underpin safety provided by automation and information technology (IT).
- Use of Memorial Sloan Kettering Cancer Center nomogram to guide intraoperative sentinel lymph node frozen sections in patients with early breast cancer. [Journal Article]
- JSJ Surg Oncol 2019 Jul 16
- CONCLUSIONS: A stratified decision-making algorithm based on the MSKCC risk prediction model improved the effectiveness of FS during SLN biopsy to avoid axillary reoperation.
- The association between ABO blood group distribution and peptic ulcer disease: a cross-sectional study from Ethiopia. [Journal Article]
- JBJ Blood Med 2019; 10:193-197
- CONCLUSIONS: Although PUD trended as more prevalent among patients with blood group O than other blood group types their association was not statistically significant.
- Moderate Chronic Ischemic Mitral Regurgitation. [Journal Article]
- IHInt Heart J 2019 Jul 12
- The benefits of concomitant mitral valve procedure (MVP) for treating moderate chronic ischemic mitral regurgitation (IMR) during coronary artery bypass grafting (CABG) have not been clearly establis…
The benefits of concomitant mitral valve procedure (MVP) for treating moderate chronic ischemic mitral regurgitation (IMR) during coronary artery bypass grafting (CABG) have not been clearly established. This study aimed to determine the incidence of moderate or more residual mitral regurgitation (MR) following CABG plus MVP for moderate chronic IMR, and to evaluate the impacts of concomitant MVP vs. CABG alone on clinical outcomes based on propensity-matched data.All eligible patients were entered into either the MVP group (CABG plus MVP, n = 184) or CABG group (CABG alone, n = 162). Moderate or more residual MR rate was investigated, and in-hospital and follow-up outcomes between the groups were compared after matching.Moderate or more residual MR rate was 11.4% at 1 year and 22.9% at 2 years after CABG plus MVP, respectively. Patients in the MVP group as compared with the CABG group had significantly lower moderate or more residual MR rates at various postoperative time points (all P < 0.001). Grouping was not an independent risk factor for in-hospital adverse events in multivariate logistic regression analysis. Also, grouping was a significant variable related to moderate or more residual MR rate and NYHA class III-IV at the latest follow-up in Cox regression analysis (HR = 0.391, 95% CI 0.114-0.628; HR = 0.419, 95% CI 0.233-0.819, respectively).Concomitant MVP as compared with CABG alone for treating moderate chronic IMR was associated with a reduction in moderate or more residual MR rate and an improvement in NYHA functional status, with no increase in in-hospital adverse events or follow-up death.
- Utilizing Quality Improvement Methods to Examine the Radiation Therapy Pathway for Patients Requiring Palliative Radiation Therapy at a Community Cancer Center. [Journal Article]
- JMJ Med Imaging Radiat Sci 2019 Jul 12
- CONCLUSIONS: The team focused on the four principles of quality improvement: the patient, team, process, and data to address the expressed discomfort around this specific radiation therapy pathway. The results dispelled some of the myths among teams and provided solutions to areas where minor improvements were required. Utilizing the data, an evidence-informed timeline was validated, encouraging task deadlines to be more evenly distributed across the pathway. Plans to monitor this pathway are being established. The team was successful in contributing to a growing culture of continuous improvement at this community cancer center.
- A new method for classifying distal radius fracture: the IDEAL classification. [Journal Article]
- RBRev Bras Ortop 2013 Jan-Feb; 48(1):36-40
- CONCLUSIONS: IDEAL classification staging rationale was presented, which is based on the best available evidence. The evidence of its scientific plausibility will be settled with the assessment of the classification reliability and its capacity to aid in therapeutical decisions and as a tool to predict prognosis. Further studies are under development to support these properties.
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- A formal model of neighborhood representation and applications in urban building aggregation supported by Delaunay triangulation. [Journal Article]
- PlosPLoS One 2019; 14(7):e0218877
- Neighborhood relationship plays an important role in spatial analysis, map generalization, co-location data mining and other applications. From the perspective of computation, the formal model of nei…
Neighborhood relationship plays an important role in spatial analysis, map generalization, co-location data mining and other applications. From the perspective of computation, the formal model of neighborhood representation is a challenging question. This study presents a formal spatial data model for representing the planar spatial field with the support of Delaunay triangulation. Based on the three geometric elements in a triangle of the vertex, edge, and triangle area, the constructed data model describes the spatial objects of a point, line, and region respectively, as well as the neighborhood relationships among them. Three types of operators based on the model are formally defined, expanding, compressing and skeletonizing. For practical applications, three complex operators are extended by continuous and conditional operation. Through the application example of urban building generalization, this study illustrates the analysis of a neighborhood relationship and the detection of spatial conflicts, which is a crucial pre-process during map generalization. With the support of the proposed formal model of neighborhood representation, the generalization method uses the three basic operations of grouping, displacement and aggregation to perform decision making and detailed operation. The generalized result can retain the balance of built-up area better than that of other similar building generalization methods.