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(haplo transplant)
3,134 results
  • Cytokine release syndrome after allogeneic stem cell transplantation with post-transplant cyclophosphamide. [Journal Article]
    Hematol Oncol. 2020 Jun 27 [Online ahead of print]Solán L, Landete E, … Kwon M
  • Cytokine release syndrome (CRS) is a systemic inflammatory response with aberrant immune activation and immune hyperstimulation, that leads to increased cytokine levels and inflammation. CRS has been described after antibody and cellular-based therapies.The use of post-transplant cyclophosphamide (PTCy) as graft-vs-host disease (GVHD) prophylaxis in haploidentical hematopoietic stem cell transpla…
  • Cord blood transplants supported by unrelated donor CD34+ progenitor cells. [Journal Article]
    Bone Marrow Transplant. 2020 Jun 09 [Online ahead of print]Gomez-Arteaga A, Orfali N, … Van Besien K
  • Alternative donor transplantation with the haplo-cord platform allows the use of a lower-dose single umbilical cord blood unit (CBU) by co-infusion of third-party CD34+-selected cells from a haploidentical relative, which provides early transient engraftment while awaiting durable CBU engraftment. In our experience, ~15% of patients lack a suitable haploidentical donor. Here we report 26 patients…
  • cGVHD in pediatric haplo-HSCT. [Journal Article]
    Biol Blood Marrow Transplant. 2020 Jun 03 [Online ahead of print]Tang FF, Cheng YF, … Wang Y
  • The specific description, risk factors, and outcomes of chronic graft-versus-host disease (cGVHD) in pediatric patients with hematological malignancies after T cell-replete (TCR) myeloablative haploidentical hematopoietic stem cell transplantation (haplo-HSCT) with anti-thymocyte globulin (ATG)/granulocyte colony-stimulating factor (G-CSF) have not been previously well described. We retrospective…
  • New insights into risk factors for transplant-associated thrombotic microangiopathy in pediatric HSCT. [Journal Article]
    Blood Adv. 2020 Jun 09; 4(11):2418-2429.Elfeky R, Lucchini G, … Veys P
  • This study aimed to identify a risk profile for development of transplant-associated thrombotic microangiopathy (TA-TMA) in children undergoing hematopoietic stem cell transplantation (HSCT). Between 2013 and 2016, 439 children underwent 474 HSCTs at 2 supraregional United Kingdom centers. At a median of 153 days post-HSCT, TA-TMA occurred among 25 of 441 evaluable cases (5.6%) with no evidence o…
  • Ten-year appraisal of pediatric renal allograft biopsies: Points to ponder. [Journal Article]
    Saudi J Kidney Dis Transpl. 2020 Mar-Apr; 31(2):482-492.Vanikar AV, Nigam LA, … Mehta AH
  • There is paucity of literature on pediatric renal allograft biopsy (RAB) evaluation. We present RAB findings of pediatric renal transplantation (RT) and correlate with outcome. This is a 10-year retrospective study of diagnostic RAB of children <12 years divided in to three groups: Group 1 (n = 9): less than haplo-match living donor RT (LDRT), Group 2 (n = 32): greater than or equal to haplo-matc…
  • The autoinflammatory side of recurrent pericarditis: Enlightening the pathogenesis for a more rational treatment. [Review]
    Trends Cardiovasc Med. 2020 May 03 [Online ahead of print]Lopalco G, Rigante D, … Iannone F
  • Recurrent pericarditis (RP) is a troublesome and debilitating complication of acute pericarditis. Although the etiopathogenesis of this condition remains unknown, an intricate overlap of autoimmune and autoinflammatory pathways has been hypothesized to explain its beginning and recurrence over time. The majority of cases are defined as "idiopathic", reflecting our awkwardness to unravel the intim…
  • Comparison of hemorrhagic and ischemic stroke after allogeneic hematopoietic stem cell transplantation. [Journal Article]
    Bone Marrow Transplant. 2020 Apr 24 [Online ahead of print]Cai X, Fu HX, … Zhang XH
  • Stroke is an important complication following allogeneic hematopoietic stem cell transplantation (allo-HSCT). Nevertheless, few studies have been published to analyzed the occurrence and prognosis of stroke after allo-HSCT. From January 2007 to December 2018 in Peking University People's Hospital, 6449 patients received HSCT and there were 2.3% of patients diagnosed with stroke after allo-HSCT (h…
  • Extraordinary claims require extraordinary evidence in asserted mtDNA biparental inheritance. [Journal Article]
    Forensic Sci Int Genet. 2020 Mar 12; 47:102274.Salas A, Schönherr S, … Weissensteiner H
  • A breakthrough article published in PNAS by Luo et al. challenges a central dogma in biology which states that the mitochondrial DNA (mtDNA) in humans is inherited exclusively from the mother. We re-analyzed original FASTQ files and results reported by Luo et al. to investigate methodological issues (e.g. nuclear mitochondrial DNA or NUMTs, DNA rearrangements) that could lead to biological misint…
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