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10,125 results
  • Iron in Health and Disease: An Update. [Journal Article]
    Indian J Pediatr 2019Lal A
  • Iron is an essential micronutrient for oxygen transport, cellular energy metabolism, and many enzymatic reactions. Complex physiological processes have evolved for iron acquisition to meet metabolic needs while avoiding toxicity from iron-generated free radicals. Systemic iron homeostasis is centered around the regulation of iron absorption from duodenum and iron release from stores by hepcidin. …
  • Bile duct involvement by hepatocellular carcinoma: A rare occurrence and poor prognostic indicator in bile duct brushing samples. [Journal Article]
    Cancer Cytopathol 2019Bhattarai S, Graham RP, … Reid MD
  • CONCLUSIONS: HCC may extend into the intrahepatic and/or extrahepatic biliary tree, causing masses and/or strictures that may be sampled on BDB. Although cytologically malignant, the classic features of HCC are uncommon, which can cause misdiagnosis. Cytopathologists should be mindful of this differential when evaluating BDBs, particularly when concomitant liver masses and/or HCC risk factors are present. Because of the associated high mortality and rapid rate of death, its presence should be conveyed clearly in pathology reports.
  • Managing the Unusual Causes of Fetal Anemia. [Journal Article]
    Fetal Diagn Ther 2019; :1-9Maisonneuve E, Ben M'Barek I, … Jouannic JM
  • CONCLUSIONS: Fetal anemia of rare or unknown diagnosis represents 5% of all transfused fetuses in our cohort. Fetal and neonatal anemias can be recurrent in further pregnancies, with variable expressivity.
  • Animal Models of Normal and Disturbed Iron and Copper Metabolism. [Journal Article]
    J Nutr 2019Wang X, Garrick MD, Collins JF
  • Research on the interplay between iron and copper metabolism in humans began to flourish in the mid-20th century, and diseases associated with dysregulated homeostasis of these essential trace minerals are common even today. Iron deficiency is the most frequent cause of anemia worldwide, leading to significant morbidity, particularly in developing countries. Iron overload is also quite common, us…
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