- Platelet-to-lymphocyte ratio (PLR) and Plateletcrit (PCT) in young patients with morbid obesity. [Journal Article]Rev Assoc Med Bras (1992) 2019; 65(9):1182-1187RA
- CONCLUSIONS: PLR or PCT may be more useful as a marker in determining an increased thrombotic state and inflammatory response in morbid obesity.
- Health assessment of Conolophus subcristatus, Conolophus pallidus, and C. subcristatus X Amblyrhynchus cristatus hybrid (Galápagos land iguanas). [Journal Article]PLoS One 2019; 14(10):e0222884Plos
- The land iguanas, Conolophus pallidus and Conolophus subcristatu are large and charismatic lizards endemic to the Galápagos archipelago, but little information exists on their normal health parameters. The former is restricted to Santa Fe island, while C. subcristatus inhabits the islands of the central and western region of the archipelago. Both species are classified as vulnerable by the IUCN R…
The land iguanas, Conolophus pallidus and Conolophus subcristatu are large and charismatic lizards endemic to the Galápagos archipelago, but little information exists on their normal health parameters. The former is restricted to Santa Fe island, while C. subcristatus inhabits the islands of the central and western region of the archipelago. Both species are classified as vulnerable by the IUCN Red List of Threatened Species. As part of a population health assessment authorized by the Galápagos National Park, wild adult iguanas from three islands (North Seymour, South Plazas, and Santa Fe) were captured in July 2018. Data from a single C. subcristatus X Amblyrhynchus cristatus hybrid captured on South Plazas is also included. We analyzed blood samples drawn from 52 healthy wild adult land iguanas captured on three islands. An iSTAT portable blood analyzer was used to obtain values for pH, lactate, pO2, pCO2, HCO3-, sO2%, hematocrit, packed cell volume (PCV), hemoglobin Na, K, iCa, and glucose. Standard laboratory hematology techniques were employed for PCV determination; resulting values were also compared to the hematocrit values generated by the iSTAT. Body temperature, heart rate, respiratory rate, and body measurements were also recorded and compared to previously published data for the marine iguana (Amblyrhynchus cristatus), which shares a common ancestor with the land iguana. The data reported here provide preliminary baseline values that may be useful in comparisons between captive and wild populations, between wild populations, and in detecting changes in health status among Galápagos land iguanas affected by anthropogenic threats, climate change, or natural disturbances.
- Timing and Outcomes of an Indication-Only Use of Intravenous Cannulation During Spontaneous Labor. [Journal Article]J Midwifery Womens Health 2019JM
- CONCLUSIONS: Indication-only IV cannulation for women experiencing an uncomplicated labor and birth is a reasonable practice in settings where IV access can be established urgently if needed.
- Validation of methods for determining pediatric midazolam using wet whole blood and volumetric absorptive microsampling. [Journal Article]Bioanalysis 2019B
- CONCLUSIONS: Validation data met internationally accepted guideline criteria. A strong correlation was observed in calculated concentrations between wet and dry test samples, indicating that VAMS is a suitable technique for use in pediatric clinical studies.
- Spontaneous splenic rupture related to anticoagulant and antiaggregant treatment. [Journal Article]Prz Gastroenterol 2019; 14(2):152-156PG
- CONCLUSIONS: Spontaneous splenic rupture is a condition that should be taken into consideration in the differential diagnosis of patients hospitalised for cardiac reasons, who are receiving anticoagulant and/or antiaggregant treatment in cases of newly developed abdominal pain and low HCT levels.
- Myocardial extracellular volume fraction to differentiate healthy from cardiomyopathic myocardium using dual-source dual-energy CT. [Journal Article]J Cardiovasc Comput Tomogr 2019JC
- CONCLUSIONS: The findings of this study resulted in a statistically significant distinction between healthy myocardium and CM ECVs. This led to the establishment of a promising threshold ECV value that could facilitate the differentiation between healthy and diseased myocardium, and highlights the potential of this DECT methodology to detect cardiomyopathic tissue.
- The Effect of Intraoperative Ferric Carboxymaltose in Joint Arthroplasty Patients: A Randomized Trial. [Journal Article]J Clin Med 2019; 8(10)JC
- This study assessed the efficacy of intraoperative high-dose intravenous iron therapy in facilitating recovery from postoperative anemia and reducing the transfusion rate in patients with total knee and total hip arthroplasty. This prospective randomized controlled study involved 58 subjects. Group F received 1000 mg intravenous ferric carboxymaltose and Group C received normal saline. The change…
This study assessed the efficacy of intraoperative high-dose intravenous iron therapy in facilitating recovery from postoperative anemia and reducing the transfusion rate in patients with total knee and total hip arthroplasty. This prospective randomized controlled study involved 58 subjects. Group F received 1000 mg intravenous ferric carboxymaltose and Group C received normal saline. The changes in hemoglobin (Hb), hematocrit, iron metabolism variables, transfusion rates, and the arterial partial pressure of oxygen and the fraction of oxygen (PaO2/FiO2) ratio were recorded. There were 29 patients of each group. The change in Hb levels from baseline to 1 month post-surgery was higher in Group F than in Group C (0.3 ± 1.0 g/dl vs. -0.8 ± 0.8 g/dl, p < 0.001). Functional iron deficiency occurred more frequently in Group C (0% vs. 48.3%, p < 0.001) after the operation. The incidence of postoperative anemia, transfusion rate and P/F ratio did not significantly differ between the two groups. This study suggests that intraoperative high-dose ferric carboxymaltose during lower limb total arthroplasty can facilitate the recovery from postoperative anemia. Although it could not prevent the occurrence of postoperative anemia or the administration of transfusion, this treatment seemed to overcome surgery-related decrease of iron availability.
- Impacts of Enriching Growing Rabbit Diets with Chlorella vulgaris Microalgae on Growth, Blood Variables, Carcass Traits, Immunological and Antioxidant Indices. [Journal Article]Animals (Basel) 2019; 9(10)A
- This work aimed to explore the effects of dietary supplementation of Chlorella vulgaris (CLV) on the growth performance, carcass traits, hematobiochemical variables, immunity responses, and the antioxidant status of growing rabbits. A total number of 100 rabbits were randomly distributed into four treatment groups, each of five replicates (25 rabbits/group). The experimental groups were as follow…
This work aimed to explore the effects of dietary supplementation of Chlorella vulgaris (CLV) on the growth performance, carcass traits, hematobiochemical variables, immunity responses, and the antioxidant status of growing rabbits. A total number of 100 rabbits were randomly distributed into four treatment groups, each of five replicates (25 rabbits/group). The experimental groups were as follows; control: a basal diet without supplementation, CLV0.5: basal diet + 0.5 g chlorella powder/kg diet; CLV1.0: basal diet + 1.0 g chlorella powder/kg diet, CLV1.5: basal diet + 1.5 g chlorella powder/kg diet. Live body weight (LBW), cumulative body weight gain (CBWG), feed intake (FI), and feed conversion ratio (FCR) were not affected by dietary CLV supplementation. Platelet count (PLT), hematocrit (HCT), means corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC) values were significantly increased in the CLV0.5 group compared with the other treatment groups. Dietary supplementation of CLV (1.5 g/kg diet) significantly reduced the alanine aminotransferase (ALT) activity. The concentrations of serum triglycerides and very low-density lipoprotein (VLDL) were lower (p < 0.05) in the CLV-treated groups than those of the control. Supplemental CLV at all experimental levels gave the best values of immunoglobulins (IgG and IgM) and glutathione activities. Malondialdehyde (MDA) levels were lower in the animals that received CLV in their diet than those of the control group. Dietary supplementation of 1.0 g CLV/kg had the potential to enhance immune responses and antioxidant status, as well as reduce blood lipid accumulation. Therefore, it could be concluded that CLV supplementation to growing rabbit diets can improve the health status.
- Effect of Hydroxyethyl Starch Loading on Glycocalyx Shedding and Cerebral Metabolism During Surgery. [Journal Article]J Surg Res 2019; 246:274-283JS
- CONCLUSIONS: Preoperative 15 mL/kg HES loading had similar effects on systemic glycocalyx shedding in both the glioma brain and normal brain groups, although patients in the normal brain group had higher levels of plasma syndecan-1. Furthermore, the intraoperative anesthetic management may substantially influence cerebral metabolism in patients with glioma.
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- Effectiveness and Safety of Hydroxyurea in the Treatment of Sickle Cell Anaemia Children in Jos, North Central Nigeria. [Journal Article]J Trop Pediatr 2019JT
- CONCLUSIONS: Hydroxyurea is effective and safe in SCA children in Jos, Nigeria. The findings could strengthen educational programme aimed at improving the utilization of hydroxyurea among SCA children.