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92 results
  • Characteristics of methotrexate-induced stroke-like neurotoxicity. [Case Reports]
    Int J Hematol 2018; 108(6):630-636Watanabe K, Arakawa Y, … Koh K
  • Intrathecal administration of methotrexate (IT-MTX) can lead to neurotoxicity. MTX-induced neurotoxicity occasionally manifests with a stroke-like presentation that is difficult to distinguish from genuine stroke. We retrospectively reviewed records of nine patients with leukemia or lymphoma and episodes of stroke-like presentation at our institute between 2010 and 2015 for whom magnetic resonanc…
  • Haemorrhagic stroke related to the use of 4-fluoroamphetamine. [Case Reports]
    J Neurol 2018; 265(7):1607-1611Wijers CHW, Visser MC, … Croes EA
  • CONCLUSIONS: Patients using 4-FA are at risk for life-threatening health problems, including intracranial haemorrhage. Additional brain imaging should be considered in 4-FA-intoxicated patients, not only in the presence of neurological deficits, but also in the case of severe headache.
  • Acute Intravenous Calcium Antagonist for Suspected Hemiplegic Migraine - A Case Story. [Case Reports]
    Case Rep Neurol 2017 Jan-Apr; 9(1):98-105Rath CL, He J, … Wienecke T
  • Stroke mimics, like attacks of hemiplegic migraine, are challenging in acute stroke evaluation. We present a 28-year-old woman with a suspected hemiplegic migraine attack with left-sided hemiparalysis. Brain CT with perfusion imaging 1 h 54 min after symptom onset revealed hypoperfusion in the right hemisphere. The patient was treated with intravenous recombinant tissue plasminogen activator (rtP…
  • Cerebrovascular adaptations to cocaine-induced transient ischemic attacks in the rodent brain. [Journal Article]
    JCI Insight 2017; 2(5):e90809You J, Volkow ND, … Pan Y
  • Occurrence of transient ischemic attacks (TIA) and cerebral strokes is a recognized risk associated with cocaine abuse. Here, we use a rodent model along with optical imaging to study cocaine-induced TIA and the associated dynamic changes in cerebral blood flow velocity (CBFv) and cerebrovasculature. We show that chronic cocaine exposure in mice resulted in marked cortical hypoperfusion, in signi…
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