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10,523 results
  • Iron overload and arrhythmias: Influence of confounding factors. [Review]
    J Arrhythm 2019; 35(4):575-583Shizukuda Y, Rosing DR
  • Arrhythmias as a cardiac complication of iron overload (IO) have been well described for decades in the clinical literature. They are assumed to be directly associated with the myocardial accumulation of iron. However, the influence of heart failure and elevated oxidative stress, which are major arrhythmogenic confounding factors associated with IO on arrhythmias, has not been critically reviewed…
  • ACG Clinical Guideline: Hereditary Hemochromatosis. [Journal Article]
    Am J Gastroenterol 2019; 114(8):1202-1218Kowdley KV, Brown KE, … Sundaram V
  • Hereditary hemochromatosis (HH) is one of the most common genetic disorders among persons of northern European descent. There have been recent advances in the diagnosis, management, and treatment of HH. The availability of molecular diagnostic testing for HH has made possible confirmation of the diagnosis for most patients. Several genotype-phenotype correlation studies have clarified the differe…
  • Hyperferritinemia in Nonalcoholic Fatty Liver Disease: Iron Accumulation or Inflammation? [Journal Article]
    Semin Liver Dis 2019Moris W, Verhaegh P, … Koek G
  • Hyperferritinemia, observed in inflammation, iron overload as well as in combination of both, is found in ∼30% of nonalcoholic fatty liver disease (NAFLD) patients. The authors summarized the evidence regarding the potential cause of hyperferritinemia in NAFLD, as this may affect the indicated therapy. A systematic literature search was conducted in EMBASE, PubMed, MEDLINE, and the Cochrane libra…
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