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(hemoglobin E disease)
406 results
  • Comparative Proteome-Wide Analysis of Bone Marrow Microenvironment of β-Thalassemia/Hemoglobin E. [Journal Article]
    Proteomes 2019; 7(1)Ponnikorn S, Mongkolrob R, … Hongeng S
  • β-thalassemia/Hb E is a global health issue, which is characterized by a range of clinical symptoms from a mild and asymptomatic anemia to severe disorders that require transfusions from infancy. Pathological mechanisms of the disease involve the excess of unmatched alpha globin and iron overload, leading to ineffective erythropoiesis and ultimately to the premature death of erythroid precursors …
  • The shortcut strategy for beta thalassemia prevention. [Journal Article]
    Hematol Rep 2018; 10(2):7530Suwannakhon N, Pongsawatkul K, … Sanguansermsri T
  • We propose antenatal blood tests using high-resolution DNA melting (HRM) analysis for beta thalassemia mutation detection after hemoglobin A2 estimation as a modified strategy for the identification of beta thalassemia at-risk couples. Antenatal blood samples of 1,115 couples were transferred from the antenatal care clinic. Hemoglobin A2 was quantified, and proportions ≥3.5% were further assessed…
  • Moyamoya syndrome in hemoglobin E-beta thalassemia: A rare presentation and association. [Case Reports]
    J Postgrad Med 2018 Oct-Dec; 64(4):240-242Doctor PN, Choudhari A, … Merchant RH
  • Moyamoya disease is an idiopathic, nonatherosclerotic, noninflammatory, chronic progressive cerebrovascular disease characterized by bilateral stenosis or occlusion of the arteries around the circle of Willis, typically the supraclinoid internal carotid arteries, followed by extensive collateralization, which are prone to thrombosis, aneurysm, and hemorrhage. Secondary moyamoya phenomenon or moya…
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