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(herpesvirus herpes virus)
105,483 results
  • Dermatological Toxicities of Bruton's Tyrosine Kinase Inhibitors. [Review]
    Am J Clin Dermatol. 2020 Jul 01 [Online ahead of print]Sibaud V, Beylot-Barry M, … Ysebaert L
  • The development of Bruton's tyrosine kinase (BTK) inhibitors represents a major breakthrough in the treatment of chronic lymphocytic leukemia and other B cell malignancies. The first-generation inhibitor ibrutinib works by covalent irreversible binding to BTK, a non-receptor tyrosine kinase of the TEC (transient erythroblastopenia of childhood) family that plays a critical role in the B-cell rece…
  • Zoster sine herpete: a review. [Review]
    Korean J Pain. 2020 Jul 01; 33(3):208-215.Zhou J, Li J, … Cao S
  • Zoster sine herpete (ZSH) is one of the atypical clinical manifestations of herpes zoster (HZ), which stems from infection and reactivation of the varicella-zoster virus (VZV) in the cranial nerve, spinal nerve, viscera, or autonomic nerve. Patients with ZSH display variable symptoms, such as neuralgia, however, different from HZ, ZSH show no zoster, which makes clinical diagnosis difficult. ZSH …
  • Intratonsillar Detection of 27 Distinct Viruses: A Cross-Sectional Study. [Journal Article]
    J Med Virol. 2020 Jun 30 [Online ahead of print]Silvoniemi A, Mikola E, … Jartti T
  • CONCLUSIONS: This study comprehensively reports a cross-sectional view of intratonsillar virus infections in elective tonsillectomy patients in a wide age range cohort. Tonsils are a major virus reservoir for distinct herpes and respiratory viruses without a positive association with tonsillar disease or respiratory symptoms. This article is protected by copyright. All rights reserved.
  • HERQ-9 Is a New Multiplex PCR for Differentiation and Quantification of All Nine Human Herpesviruses. [Journal Article]
    mSphere. 2020 Jun 24; 5(3)Pyöriä L, Jokinen M, … Perdomo MF
  • Infections with the nine human herpesviruses (HHVs) are globally prevalent and characterized by lifelong persistence. Reactivations can potentially manifest as life-threatening conditions for which the demonstration of viral DNA is essential. In the present study, we developed HERQ-9, a pan-HHV quantitative PCR designed in triplex reactions to differentiate and quantify each of the HHV-DNAs: (i) …
  • Pregnancy and delivery in women with a high risk of infection in pregnancy. [Journal Article]
    J Matern Fetal Neonatal Med. 2020 Jun 23 [Online ahead of print]Barinov SV, Tirskaya YI, … Tshulovski YI
  • Background: Pregnant women with chronic genital and non-genital infections are at a high risk of infections complication during pregnancy and the postpartum period. Preterm birth is one of the leading causes of obstetric and neonatal complications and occurs in one in nine women. Forty per cent of preterm births are considered to be caused by the abnormal vaginal microbiome, and there is current…
  • Chemokine-binding proteins encoded by herpesviruses. [Journal Article]
    Acta Virol. 2020; 64(2):233-244.Benko M, Lenhartová S, … Kúdelová M
  • To establish infection, a wide variety of pathogens, including viruses, have evolved a number of strategies to avoid immune elimination. Viruses have acquired and optimized molecules that interact with the host chemokine network in order to disrupt immune surveillance and defense of vertebrates, helping to promote cell entry, facilitating dissemination of infected cells, and evasion the immune re…
  • Primary effusion lymphoma metachronous to multicentric Castleman disease in an immunocompetent patient. [Case Reports]
    Pathol Res Pract. 2020 Jul; 216(7):153024.Parente P, Zanelli M, … Graziano P
  • Human Herpesvirus 8 (HHV8) has been associated with a wide spectrum of B-cell lymphoproliferative disorders, including Primary Effusion Lymphoma, Multicentric Castleman Disease, HHV8-positive Diffuse Large B-cell Lymphoma, not otherwise specified and germinotropic lymphoproliferative disorder. The association of different HHV8-related lymphoproliferative disorders is described in immunodeficient …
  • Ivermectin: a systematic review from antiviral effects to COVID-19 complementary regimen. [Review]
    J Antibiot (Tokyo). 2020 Jun 12 [Online ahead of print]Heidary F, Gharebaghi R
  • Ivermectin proposes many potentials effects to treat a range of diseases, with its antimicrobial, antiviral, and anti-cancer properties as a wonder drug. It is highly effective against many microorganisms including some viruses. In this comprehensive systematic review, antiviral effects of ivermectin are summarized including in vitro and in vivo studies over the past 50 years. Several studies rep…
  • Human Herpesvirus 6 Associated Encephalitis with Fulminant Brain Edema in a Previously Healthy Child. [Case Reports]
    Cureus. 2020 May 07; 12(5):e8018.Sevilla-Acosta F, Araya-Amador J, Ulate-Campos A
  • Human herpesvirus 6 (HHV-6) is an important cause of roseola and febrile seizures in children. However, it is also a rare cause of encephalitis, most common in immunosuppressed children. We describe a case of HHV-6 encephalitis with fulminant brain edema in a previously healthy child. This severe HHV-6 clinical case with lethal brain edema is the second reported in the literature in a previously …
  • Extracellular Vesicles in Viral Spread and Antiviral Response. [Review]
    Viruses. 2020 Jun 08; 12(6)Bello-Morales R, Ripa I, López-Guerrero JA
  • Viral spread by both enveloped and non-enveloped viruses may be mediated by extracellular vesicles (EVs), including microvesicles (MVs) and exosomes. These secreted vesicles have been demonstrated to be an efficient mechanism that viruses can use to enter host cells, enhance spread or evade the host immune response. However, the complex interplay between viruses and EVs gives rise to antagonistic…
  • [Ancient variants of the Epstein-Barr virus (Herpesviridae, Lymphocryptovirus, HHV-4): hypotheses and facts.] [Journal Article]
    Vopr Virusol. 2020; 65(2):77-86.Smirnova KV, Senyuta NB, … Gurtsevich VE
  • CONCLUSIONS: Analysis of LMP1 sequences from washings of the Slavs oral cavity demonstrated the presence of LMP1 variants with varying degrees of transforming potential: B98.5/A, China1, Med-, and NC. The analysis of LMP1 sequences from washings of Tatar oral cavity also made it possible to identify oncoprotein variants such as B95.8/A, China1, Med-, as well as a group of variants out of classifications (LMP1-OK). An important finding was the identification of 7 variants of LMP1 from Tatars, designated as LMP1-TatK, that contained two unique deletions of 5 aa in codons 312-316 and 382-386, which were absent in the LMP1 variants from Slavs and from previously examined cancer patients and healthy individuals, as well as in sequences from open computer databases. The uniqueness of the LMP1-TatK variant is confirmed both by phylogenetic analysis of LMP1 sequences of Tatar origin and by the analysis of 11 aa repeats and 5 aa insertions in the C-terminal region of the oncoprotein. The morbidity and mortality rates from neoplasms, including EBV-associated pathologies, did not differ significantly between two studied ethnic groups infected with different EBV strains.The data obtained allowed us to suggest that: 1) LMP1-TatK could be refered to an evolutionarily ancient EBV strain that persists among Tatars and; 2) LMP1-TatK belongs to the so-called "Volga" EBV virus strain, the common strain among the population of the Volga region. Extended studies of EBV isolates from residents of this region may probably shed the light on the origin of LMP1-TatK.
  • From Conifers to Cognition: Microbes, Brain, and Behavior. [Review]
    Genes Brain Behav. 2020 Jun 09 [Online ahead of print]Lathe R, St Clair D
  • A diversity of bacteria, protozoans, and viruses ('endozoites') were recently uncovered within healthy tissues including the human brain. By contrast, it was already recognized a century ago that healthy plants tissues contain abundant endogenous microbes ('endophytes'). Taking endophytes as an informative precedent, we overview the nature, prevalence, and role of endozoites in mammalian tissues,…
  • A tissue level atlas of the healthy human virome. [Journal Article]
    BMC Biol. 2020 Jun 04; 18(1):55.Kumata R, Ito J, … Sato K
  • CONCLUSIONS: To our knowledge, this study is the first comprehensive investigation of the human virome in a variety of tissues in healthy individuals through meta-transcriptomic analysis. Further investigation of the associations described here, and application of this analytical pipeline to additional datasets, will be useful to reveal the impact of viral infections on human health.
  • Recurrent extragenital herpes simplex type 2 occurring in a distal location of the same dermatome. [Case Reports]
    IDCases. 2020; 21:e00783.Eksomtramage T, Aiempanakit K
  • Herpes simplex infection (HSV) is a common infectious disease, which the main clinical manifestations are mucocutaneous infection. Extragenital infections are reported in both type 1 and type 2 of herpes simplex virus. We report a case of a 33-year-old female with recurrent extragenital HSV type 2 infection on the right medial wrist. The patient had history of the previous infection site locating…
  • [Different viral doses of cytomegalovirus infection in the left and right colons]. [Journal Article]
    Zhonghua Bing Li Xue Za Zhi. 2020 Jun 08; 49(6):583-587.Wang XZ, Yang H, … Zhou WX
  • Objective: To compare the differences in the detection rates of cytomegalovirus (CMV) infection between the left and right colons for guiding endoscopic biopsy-sites. Methods: The cases of colonic CMV infection confirmed by histology at the Peking Union Medical College Hospital from July 2015 to July 2018 were collected and analyzed. Splenic curvature was used as the dividing point between the …
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