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(humor therapy)
7,534 results
  • Proteomic Biomarkers of Retinal Inflammation in Diabetic Retinopathy. [Review]
    Int J Mol Sci 2019; 20(19)Youngblood H, Robinson R, … Sharma S
  • Diabetic retinopathy (DR), a sight-threatening neurovasculopathy, is the leading cause of irreversible blindness in the developed world. DR arises as the result of prolonged hyperglycemia and is characterized by leaky retinal vasculature, retinal ischemia, retinal inflammation, angiogenesis, and neovascularization. The number of DR patients is growing with an increase in the elderly population, a…
  • Immune Mediated Degeneration and Possible Protection in Glaucoma. [Review]
    Front Neurosci 2019; 13:931Tsai T, Reinehr S, … Joachim SC
  • The underlying pathomechanisms for glaucoma, one of the most common causes of blindness worldwide, are still not identified. In addition to increased intraocular pressure (IOP), oxidative stress, excitotoxicity, and immunological processes seem to play a role. Several pharmacological or molecular/genetic methods are currently investigated as treatment options for this disease. Altered autoantibod…
  • The Humor in Therapy: the Healing Power of Laughter. [Journal Article]
    Psychiatr Danub 2019; 31(Suppl 3):503-508Amici P
  • Although humour is a key element of human communication, and, for this reason, it is also present in therapeutic contexts, its use in this sense still remains largely untapped. The purpose of this article is to increase curiosity and broaden the reflection on the use of humour in the psychotherapeutic relationship. The first part is dedicated to a short review of the main theories on the origins …
  • Mitochondrial-Targeted Antioxidants Attenuate TGF-β2 Signaling in Human Trabecular Meshwork Cells. [Journal Article]
    Invest Ophthalmol Vis Sci 2019; 60(10):3613-3624Rao VR, Lautz JD, … Stubbs EB
  • CONCLUSIONS: The multifunctional profibrotic cytokine TGF-β2 elicits a marked increase in oxidative stress in human TM cells. Mitochondrial-targeted antioxidants attenuate TGF-β2-mediated changes in Smad-dependent transcriptional activity, including marked reductions in CTGF and collagen isoform gene and protein expression. These findings suggest that mitochondrial-targeted antioxidants, when delivered directly to the TM, exhibit potential as a novel strategy by which to slow the progression of TGF-β2-mediated remodeling of the ECM within the TM.
  • Addressing Evidence Linking Secondary Alexithymia to Aberrant Humor Processing. [Review]
    Behav Neurol 2019; 2019:1803624Patrikelis P, Lucci G, … Gatzonis S
  • In this review, we explore current literature and assess evidence linking secondary (acquired) alexithymia to aberrant humor processing, in terms of their neurobiological underpinnings. In addition, we suggest a possible common neuropathological substrate between secondary alexithymia and deficits in humor appreciation, by drawing on neurophysiologic and neuroradiological evidence, as well as on …
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