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32,819 results
  • Fetal and neonatal neurogenetics. [Journal Article]
  • HCHandb Clin Neurol 2019; 162:105-132
  • Jansen AC, Keymolen K
  • Disorders of the developing nervous system may be of genetic origin, comprising congenital malformations of spine and brain as well as metabolic or vascular disorders that affect normal brain develop…
  • Muenke syndrome: long-term outcome of a syndrome-specific treatment protocol. [Journal Article]
  • JNJ Neurosurg Pediatr 2019 Jul 19; :1-8
  • den Ottelander BK, de Goederen R, … Mathijssen IMJ
  • CONCLUSIONS: Patients with Muenke syndrome treated with a single fronto-supraorbital advancement in their first year of life rarely develop signs of intracranial hypertension, in accordance with the very low prevalence of its causative factors (OSA, hydrocephalus, and restricted skull growth). This illustrates that there is no need for a routine second craniofacial procedure. Patient follow-up should focus on visual assessment and speech and hearing outcomes.
  • Feasibility of fast brain diffusion MRI to quantify white matter injury in pediatric hydrocephalus. [Journal Article]
  • JNJ Neurosurg Pediatr 2019 Jul 19; :1-8
  • Isaacs AM, Shimony JS, … Limbrick DD
  • CONCLUSIONS: The utility of fast brain MRI can be extended beyond anatomical assessments to obtain dMRI measures. A reduction in PLIC and gCC MD to levels similar to those of controls was observed within 14 months following shunt surgery for hydrocephalus in PHH and CH infants. Further studies are required to assess the role of fast brain dMRI for assessing clinical outcomes in pediatric hydrocephalus patients.
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