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30,494 results
  • Antiphospholipid syndrome's genetic and epigenetic aspects. [Review]
  • ARAutoimmun Rev 2019 Jul 16; :102352
  • Iuliano A, Galeazzi M, Sebastiani GD
  • Studies on last genetic and epigenetic predisposition to APS are summarized. It is well known that genetic predisposition is in HLA system (DR4 and DRw53) and that lupus anticoagulant (LA) and antica…
  • Hereditary thrombophilia genetic variants in recurrent pregnancy loss. [Journal Article]
  • AGArch Gynecol Obstet 2019 Jul 17
  • Ahangari N, Doosti M, … Ghayoor Karimiani E
  • CONCLUSIONS: The allele frequencies for the assessed genotypes in this study are consistent with the data obtained for other countries. We observed significant susceptible effects of MTHFR C677T, and A1298C among participants. According to the relatively high prevalence of these variants, we recommend genetic testing for women with RPL before therapeutic decisions.
  • Risk of bleeding and thrombosis in inherited qualitative fibrinogen disorders. [Journal Article]
  • EJEur J Haematol 2019 Jul 17
  • Castaman G, Giacomelli SH, … Radossi P
  • CONCLUSIONS: This study confirms the heterogeneity of clinical features in inherited dysfibrinogenemia, due to the wide spectrum of the causative mutations. Larger multicenter studies are needed to assess the definitive correlation of some mutations with bleeding or thrombosis. This article is protected by copyright. All rights reserved.
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