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116,780 results
  • Anti IL-17 in psoriasis. [Journal Article]
    Expert Rev Clin Immunol 2019Ly K, Smith MP, … Bhutani T
  • Introduction: Psoriasis is a chronic, immune-mediated disease with significant associated comorbidities. Its pathogenesis is likely multifactorial, however, the interleukin-23/T helper 17 pathway has been identified as a critical axis in its pathogenesis. Interleukin-17A is the primary effector of this pathway and overexpression of IL-17A results in epidermal hyperplasia and an overly robust infl…
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