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Unbound Medicine.
(hypo hyp )
10 results
  • L-Hydroxyproline and d-Proline Catabolism in Sinorhizobium meliloti. [Journal Article]
    J Bacteriol. 2016 Feb 01; 198(7):1171-81.Chen S, White CE, … Finan TM
  • Sinorhizobium meliloti forms N2-fixing root nodules on alfalfa, and as a free-living bacterium, it can grow on a very broad range of substrates, including l-proline and several related compounds, such as proline betaine, trans-4-hydroxy-l-proline (trans-4-l-Hyp), and cis-4-hydroxy-d-proline (cis-4-d-Hyp). Fourteen hyp genes are induced upon growth of S. meliloti on trans-4-l-Hyp, and of those, hy…
  • Control of hydroxyproline catabolism in Sinorhizobium meliloti. [Journal Article]
    Mol Microbiol. 2012 Sep; 85(6):1133-47.White CE, Gavina JM, … Finan TM
  • Hydroxyproline (Hyp) in decaying organic matter is a rich source of carbon and nitrogen for microorganisms. A bacterial pathway for Hyp catabolism is known; however, genes and function relationships are not established. In the pathway, trans-4-hydroxy-L-proline (4-L-Hyp) is epimerized to cis-4-hydroxy-D-proline (4-D-Hyp), and then, in three enzymatic reactions, the D-isomer is converted via Δ-pyr…
  • Hypo, hype and 'hyp' human proteins. [Journal Article]
    Bioinformation. 2007 Jul 10; 2(1):31-3.Suravajhala P
  • Genes with unknown function are called orphan genes while their transcripts and peptides are called hypothetical proteins. There are many genes and their associated proteins that remain uncharacterized in the human genome. A database of human hypothetical proteins with ascribed functions could be helpful for biologists to search for potential proteins of interest. In recent years, the rapid compl…
  • Dentinal defects in Hyp mice not caused by hypophosphatemia alone. [Journal Article]
    Arch Oral Biol. 2006 Jan; 51(1):58-63.Ogawa T, Onishi T, … Ooshima T
  • The Hyp mouse is a murine homolog of human X-linked hypophosphatemic rickets and displays hypo-mineralization in bone and dentin due to a defect of the phosphate-regulating gene with homology to endopeptidase on the X chromosome (Phex) gene. It has long been considered that the bone and dentin defects in Hyp mice are caused by hypophosphatemia alone, however, several recent studies have indicated…
  • Size mismatch effects in oxide solid solutions using Monte Carlo and configurational averaging. [Journal Article]
    Phys Chem Chem Phys. 2005 Mar 21; 7(6):1127-35.Mohn CE, Lavrentiev MY, … Stølen S
  • Local minima configurational averaging (CA) and Monte Carlo (MC) simulations are used to examine in detail the variation of thermodynamic and structural properties of binary oxide solid solutions with the volume mismatch between the end members. The maximum volume mismatch studied corresponds to that in the CaO MgO solid solution, a prototype example of a strongly non-ideal system with large misc…
  • Hyper-expression of osteocalcin mRNA in odontoblasts of Hyp mice. [Journal Article]
    J Dent Res. 2005 Jan; 84(1):84-8.Onishi T, Ogawa T, … Ooshima T
  • The Hyp mouse is a murine homologue of human X-linked hypophosphatemia that displays hypo-mineralization in bone and dentin. In this study, we tested the hypothesis that the defect in Hyp mice leads to alterations in the expression of dentin matrix proteins that may be associated with the hypo-mineralization changes in the tissues. Quantitative RT-PCR analyses showed that expression of the osteoc…
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