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504 results
  • Oral adverse effects of drugs: taste disorders. [Journal Article]
    Oral Dis 2019Rademacher WMH, Aziz Y, … Rozema FR
  • CONCLUSIONS: Healthcare professionals are frequently confronted with drugs reported to cause taste disorders. This article provides an overview of these drugs to support clinicians in their awareness, diagnosis and treatment of drug-induced taste disorders.
  • Association of oral toxicity and taste changes during hematopoietic stem cell transplantation: a preliminary study. [Journal Article]
    Support Care Cancer 2019Ferreira MH, Mello Bezinelli L, … Corrêa L
  • CONCLUSIONS: Frequency of hypogeusia was high in the neutropenia period of the HCT. None of the taste changes was determined by oral mucositis, tongue depapillation, or reduced salivary flow, but melphalan conditioning reduced the bitter taste sensation. Loss of body weight and poor quality of life were associated with taste changes and reduced salivary flow. Further studies are necessary to elucidate this association and the risk factors for taste changes in HCT.
  • Gustatory Function of Pregnant and Nonpregnant Women in a Tertiary Health Institution. [Journal Article]
    Ear Nose Throat J 2019; 98(3):143-148Fasunla AJ, Nwankwo U, … Nwaorgu OG
  • Physiological changes in pregnancy may cause taste dysfunction. The aim of this study was to determine and compare gustatory function of pregnant women with nonpregnant women and also to investigate the effect of pregnancy on gustatory function. It was a case-control study of consecutive 70 healthy pregnant women (cases) and 70 healthy nonpregnant women (control). Participants scored their taste …
  • 74 Alpha Lipoic Acid Responsive Hypergeusia. [Journal Article]
    CNS Spectr 2019; 24(1):212-213Cormie SE, Hirsch AR
  • IntroductionImprovement in hypergeusia in response to alpha lipoic acid treatment has not heretofore been described. Such a case is presented. METHODS: Case Study: A 64 year old right handed nasute female noted the sudden onset of salty hypergeusia, about 200% saltier than foods should be. Concurrently she experienced a constant phantogeusia of salt involving the front half of her tongue, lips, …
  • 24 CerefolinNAC Therapy-Induced Dysgeusia. [Journal Article]
    CNS Spectr 2019; 24(1):186Nayati JT, Chaudhry FS, … Hirsch AR
  • CONCLUSIONS: When treating taste impairments, vitamins and minerals have been found to enhance the effect of non-injured nerves, but they do not repair damaged nerves. The presence of a scalloped tongue may suggest nerve injury of unknown proportion, and can either diminish or alter taste. CFLN-NAC may have enhanced the gustatory stimulus of the non-injured nerves. This transient increase could have either caused her dysgeusia or possibly unmasked the dysgeusia secondary to a scalloped tongue. Notable impairments found in her exam evince Parkinson's disease as a possible etiology, but structural abnormalities were not seen on brain MRI, making this unlikely. Conversely, the relatively rapid resolution after terminating CFLN-NAC strongly suggests that this is not merely a coincidence, but rather an origin. Those initiated on CFLN-NAC should be queried for new onset of dysgeusia and warrant other treatment options.Funding Acknowledgements: Smell & Taste Treatment and Research Foundation.
  • Distorted Taste and Impaired Oral Health in Patients with Sicca Complaints [Journal Article]
    Nutrients 2019; 11(2)Singh PB, Young A, … Jensen JL
  • Senses of smell and taste, saliva flow, and dental status are considered as important factors for the maintenance of a good nutritional status. Salivary secretory rates, chemosensory function, burning mouth sensation, halitosis and dental status were investigated in 58 primary Sjögren's syndrome (pSS) patients, 22 non-Sjögren's syndrome sicca (non-SS) patients, and 57 age-matched healthy controls…
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