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(immune globulin)
872,594 results
  • Immunomodulatory and Prebiotic Effects of 2'-Fucosyllactose in Suckling Rats. [Journal Article]
    Front Immunol 2019; 10:1773Azagra-Boronat I, Massot-Cladera M, … Pérez-Cano FJ
  • Human milk oligosaccharides are unconjugated complex glycans present in high concentration in human milk that serve as pre-biotics and immunomodulators. They are not primarily absorbed or metabolized by the infant and reach the lower part of the intestinal tract unaltered. One of the main oligosaccharides found in human milk is 2'-fucosyllactose (2'-FL). This study aimed to investigate the effect…
  • Iatrogenic antibody deficiency from B-cell targeted therapies in autoimmune rheumatic diseases. [Journal Article]
    Lupus Sci Med 2019; 6(1):e000337Wijetilleka S, Jayne D, … Karim MY
  • B-cell targeted therapies (BCTT) are now widely used in autoimmune rheumatic diseases, including SLE, antineutrophil cytoplasmic antibody-associated vasculitis and rheumatoid arthritis. Early studies suggested that rituximab did not influence serum immunoglobulins. However, subsequently, with increased patient numbers, longer follow-up duration and many patients having received multiple BCTT cour…
  • Epitope Mapping of Tetanus Toxin by Monoclonal Antibodies: Implication for Immunotherapy and Vaccine Design. [Review]
    Neurotox Res 2019Ghotloo S, Golsaz-Shirazi F, … Shokri F
  • Tetanus as a life-threatening disease is characterized by muscle spasm. The disease is caused by the neurotoxin of Clostridium tetani. Active form of tetanus neurotoxin is composed of the light chain (fragment A) and the heavy chain. Fragment A is a zinc metalloprotease, which cleaves the neuronal soluble N-ethylmaleimide-sensitive attachment receptor (SNARE) protein, leading to the blockade of i…
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