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1,717,443 results
  • StatPearls: Coombs Test [BOOK]
    StatPearls Publishing: Treasure Island (FL) Theis Samuel R. SR Wright-Patterson AFB / Wright State Hashmi Muhammad F. MF College of Physicians and Surgeons BOOK
  • Antiglobulin testing, also known as the Coombs test, is an immunology laboratory procedure used to detect the presence of antibodies against circulating red blood cells (RBCs) in the body, which then induce hemolysis. The destruction of these red blood cells (RBCs) by antibodies directed against them is described diagnostically as autoimmune hemolytic anemia (AIHA). Many etiologies fall under thi…
  • A customizable microfluidic platform for medium-throughput modeling of neuromuscular circuits. [Journal Article]
    Biomaterials 2019; 225:119537Bellmann J, Goswami RY, … Sterneckert J
  • Neuromuscular circuits (NMCs) are vital for voluntary movement, and effective models of NMCs are needed to understand the pathogenesis of, as well as to identify effective treatments for, multiple diseases, including Duchenne's muscular dystrophy and amyotrophic lateral sclerosis. Microfluidics are ideal for recapitulating the central and peripheral compartments of NMCs, but myotubes often detach…
  • Tissue-specific expression of IgG receptors by human macrophages ex vivo. [Journal Article]
    PLoS One 2019; 14(10):e0223264Bruggeman CW, Houtzager J, … Kuijpers TW
  • Recently it was discovered that tissue-resident macrophages derive from embryonic precursors, not only from peripheral blood monocytes, and maintain themselves by self-renewal. Most in-vitro studies on macrophage biology make use of in-vitro cultured human monocyte-derived macrophages. Phagocytosis of IgG-opsonized particles by tissue-resident macrophages takes place via interaction with IgG rece…
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