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14,108 results
  • The risk of uveitis in patients with JIA receiving etanercept: the challenges of analysing real-world data. [Journal Article]
    Rheumatology (Oxford) 2019Davies R, Cock D, … British Society for Paediatric and Adolescent Rheumatology Etanercept Cohort Study (BSPAR-ETN) and the Biologics for Children with Rheumatic Diseases (BCRD) study
  • CONCLUSIONS: In this first paper to compare the rate of new onset uveitis across the three main anti-TNF therapies used in JIA, a new diagnosis of uveitis is less common among patients starting biologics compared with MTX, although this did not reach statistical significance. The suggested protective effect of etanercept is likely explained by confounding, whereby patients in the MTX cohort are younger and earlier in disease, and therefore at greater risk of developing uveitis compared with etanercept patients.
  • Certolizumab Pegol Treatment in Three Patients With Takayasu Arteritis. [Case Reports]
    Arch Rheumatol 2019; 34(3):357-362Ataş N, Varan Ö, … Tufan A
  • Although glucocorticoids are the mainstay of treatment in Takayasu arteritis (TA), anti-tumor necrosis factor agents are other treatment options in refractory disease. The onset of TA is generally observed in females of reproductive age. Certolizumab pegol (CZP) lacks a fragment crystallizable region and this gives advantage of minimal transfer through the placenta, which makes CZP a safer option…
  • Hidradenitis Suppurativa. [Journal Article]
    Dis Colon Rectum 2019; 62(11):1278-1280Kawak S
  • A 66-year-old obese (BMI 34) diabetic man, a former smoker who had quit 4 months ago, had a 20-year history of perianal, inguinal, and gluteal hidradenitis suppurativa. He presented to the office with persistent perianal and gluteal inflammation and drainage. He had had various surgical excisions of the affected area over the preceding 10 years. The patient was also following up with dermatology …
  • Immune checkpoint inhibitor-induced diarrhea: A clinicopathological study of eleven patients. [Case Reports]
    Dig Endosc 2019Yanai S, Nakamura S, … Matsumoto T
  • We reviewed the records of patients with immune checkpoint inhibitors (ICI)-induced diarrhea during 2015-2019. The ICIs included nivolumab and ipilimumab. There were 11 patients with ICI-induced diarrhea with ages 46-81 years (median, 63 years). On colonoscopy, four patients showed normal, while loss of vascularity, erythema, granularity, erosions or ulcerations apparently mimicking ulcerative co…
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