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44,146 results
  • Glucocorticoids increase renal excretion of urate in mice by down-regulating urate transporter 1. [Journal Article]
    Drug Metab Dispos 2019Li G, Han L, … Zhang Y
  • Both non-steroidal anti-inflammatory drugs (NSAIDs) and glucocorticoids have been widely used for the treatment of gout, a disease promoted by excess body burden of uric acid (UA). However, their effects on the homeostasis of UA remain poorly understood. The present study showed that 1-week treatments with three NSAIDs (ibuprofen, diclofenac and indomethacin) had little effect on UA homeostasis i…
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